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Francesc Villarroya
University of Barcelona
106Publications
31H-index
2,871Citations
Publications 106
Newest
#1Marta Díaz (University of Barcelona)H-Index: 23
#2Laura Campderros (University of Barcelona)H-Index: 2
Last.Lourdes Ibáñez (University of Barcelona)H-Index: 57
view all 7 authors...
Growth-and-differentiation-factor-15 (GDF15) is a regulator of energy homeostasis. To determine the relationship between circulating GDF15 and parameters of metabolic health, we assessed longitudinally GDF15 concentrations in infants born either appropriate- (AGA) or small-for-gestational-age (SGA), the latter population known to be at risk for metabolic alterations, particularly after a rapid postnatal catch-up in weight. The study cohort consisted of 103 infants (70 AGA and 33 SGA). Assessment...
#1Rubén Cereijo (University of Barcelona)H-Index: 11
#2Siri D. TaxeråsH-Index: 1
view all 13 authors...
Introduction miRNAs are small non-coding RNAs, some of which are expressed in adipose tissues, are present in the circulation, and are regulated in obesity. Bariatric surgery (BS) has been proposed to lead to activation of brown adipose tissue, an effect that may be related to beneficial effects of BS on systemic metabolism. Here, we evaluated circulating levels of miR-92a and miR-99b, two miRNAs proposed as biomarkers of brown fat activity, in a cohort of patients with severe obesity before and...
#1Carlos Casasnovas (Bellvitge University Hospital)H-Index: 3
#2Manuel RuizH-Index: 13
Last.Aurora PujolH-Index: 35
view all 18 authors...
X-Adrenoleukodystrophy (X-ALD) and its adult-onset, most prevalent variant adrenomyeloneuropathy (AMN) are caused by mutations in the peroxisomal transporter of the very long-chain fatty acid ABCD1. AMN patients classically present spastic paraparesis that can progress over decades, and a satisfactory treatment is currently lacking. Oxidative stress is an early culprit in X-ALD pathogenesis. A combination of antioxidants halts the clinical progression and axonal damage in a murine model of AMN, ...
#1Rita Malpique (University of Barcelona)H-Index: 3
#2José M. Gallego-Escuredo (University of Barcelona)H-Index: 14
Last.Lourdes Ibáñez (University of Barcelona)H-Index: 57
view all 8 authors...
Individuals born small-for-gestational age (SGA), especially those who experience postnatal catch-up growth, are at increased risk for developing endocrine-metabolic abnormalities before puberty. In adults, brown adipose tissue (BAT) has been associated with protection against metabolic disorders, such as obesity, type 2 diabetes, and dyslipidaemia. Here, we assessed for the first time whether BAT activation differs between prepubertal children born SGA or appropriate-for-gestational age (AGA). ...
#1David Sánchez-Infantes (University of Barcelona)H-Index: 9
#2Rubén Cereijo (University of Barcelona)H-Index: 11
Last.Lourdes Ibáñez (University of Barcelona)H-Index: 57
view all 6 authors...
Background. Nerve growth factor (NGF) plays a key role in neuroprotection and developmental maturity. We assessed longitudinally the circulating concentrations of NGF in term healthy human newborns and infants as well as their association with prenatal growth and early postnatal feeding patterns. Methods. Circulating NGF and anthropometric measures (weight, length, body mass index, and ponderal index) were assessed longitudinally—at birth and at age 4 months—in 86 term infants born appropriate (...
#1Francesc Villarroya (University of Barcelona)H-Index: 31
#2Rubén Cereijo (University of Barcelona)H-Index: 11
Last.Marta Giralt (University of Barcelona)H-Index: 43
view all 5 authors...
#1Marta Díaz (University of Barcelona)H-Index: 23
#2José M. Gallego-Escuredo (University of Barcelona)H-Index: 14
Last.Lourdes Ibáñez (University of Barcelona)H-Index: 57
view all 6 authors...
Background. Fetuin-A is a glycoprotein produced in the liver and related to metabolic syndrome; fetuin-A secretion is divergently regulated in different pathological conditions. In girls with polycystic ovary syndrome (PCOS), insulin sensitization results in a more favorable endocrine-metabolic outcome than oral contraception; we assessed whether those differences are underscored by changes in circulating fetuin-A. Methods. Fetuin-A concentration endocrine-metabolic markers and hepatovisceral fa...
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