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Natalia R. Kunst
Yale University
EconometricsObservational studyDecision modelExpected value of sample informationValue of information
4Publications
0Citations
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Publications 7
Newest
#1Anna Heath (UCL: University College London)
#1Anna Heath (UCL: University College London)H-Index: 4
Last. Hawre Jalal (University of Pittsburgh)H-Index: 8
view all 9 authors...
Background. Investing efficiently in future research to improve policy decisions is an important goal. Expected value of sample information (EVSI) can be used to select the specific design and samp...
Source
#1Scott D. Grosse (CDC: Centers for Disease Control and Prevention)H-Index: 47
#2Natalia R. Kunst (Yale University)
Last. Torbjørn Wisløff (University of Oslo)H-Index: 15
view all 5 authors...
#1Jeremy D. Goldhaber-Fiebert (Stanford University)H-Index: 29
#2Anna Heath (U of T: University of Toronto)H-Index: 4
Last. Natalia R. Kunst (Yale University)
view all 5 authors...
#1Anna Heath (U of T: University of Toronto)
#2Hawre Jalal (University of Pittsburgh)H-Index: 8
Last. Natalia R. Kunst (Yale University)
view all 5 authors...
Objectives: Value of information (VOI) analyses can help policy-makers make informed decisions about whether to conduct and how to design future studies. Historically, a computationally expensive method to compute the Expected Value of Sample Information (EVSI) restricted the use of VOI to simple decision models and study designs. Recently, four EVSI approximation methods have made such analyses more feasible and accessible. We provide practical recommendations for analysts computing EVSI by eva...
Last. Shi-Yi Wang (Yale University)H-Index: 16
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Abstract Objectives The 21-gene assay Oncotype DX (21-GA) shows promise as a guide in deciding when to initiate adjuvant chemotherapy in women with hormone receptor–positive early-stage breast cancer. Nevertheless, its routine use remains controversial, owing to insufficient evidence of its clinical utility and cost-effectiveness. Accordingly, we aim to quantify the value of conducting further research to reduce decision uncertainty in the use of the 21-GA. Methods Using value of information met...
Source
#1Anna HeathH-Index: 4
Last. Hawre JalalH-Index: 8
view all 9 authors...
Investing efficiently in future research to improve policy decisions is an important goal. Expected Value of Sample Information (EVSI) can be used to select the specific design and sample size of a proposed study by assessing the benefit of a range of different studies. Estimating EVSI with the standard nested Monte Carlo algorithm has a notoriously high computational burden, especially when using a complex decision model or when optimizing over study sample sizes and designs. Therefore, a numbe...
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