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Beomhee Kim
Seoul National University
Synthetic biologyWhole genome sequencingPediococcus acidilacticiGeneticsBiology
3Publications
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Publications 4
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#1Jaewoo Yim (SNU: Seoul National University)H-Index: 1
#2Sung Won Cho (SNU: Seoul National University)
Last. Sang Woo SeoH-Index: 17
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Long-term space missions affect the gut microbiome of astronauts, especially the viability of some pathogens. Probiotics may be an effective solution for the management of gut microbiomes, but there is a lack of studies regarding the physiology of probiotics in microgravity. Here, we investigated the effects of microgravity on the probiotic Escherichia coli Nissle 1917 (EcN) by comparing transcriptomic data during exponential and stationary growth phases under simulated microgravity and normal g...
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#1Sung Won Cho (SNU: Seoul National University)
#2Jina Yang (SNU: Seoul National University)H-Index: 8
Last. Sang Woo Seo (SNU: Seoul National University)H-Index: 17
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Pediococcus acidilactici is a probiotic bacterium that is industrially utilized in the food industry and antibiotics development. Here, we determine the complete nucleotide sequence of the genome of Pediococcus acidilactici ATCC 8042. The genome was sequenced by the PacBio RSII to generate a single contig consisting of circular chromosome sequence. Illumina MiniSeq sequencing platform and Sanger sequencing method were additionally utilized to correct errors resulting from the long-read sequencin...
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#1Hyun Gyu Lim (POSTECH: Pohang University of Science and Technology)H-Index: 8
#2Dong Hun Kwak (POSTECH: Pohang University of Science and Technology)H-Index: 1
Last. Gyoo Yeol Jung (POSTECH: Pohang University of Science and Technology)H-Index: 27
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Although brown macroalgae holds potential as an alternative feedstock, its utilization by conventional microbial platforms has been limited due to the inability to metabolize one of the principal sugars, alginate. Here, we isolate Vibrio sp. dhg, a fast-growing bacterium that can efficiently assimilate alginate. Based on systematic characterization of the genomic information of Vibrio sp. dhg, we establish a genetic toolbox for its engineering. We also demonstrate its ability to rapidly produce ...
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#1Jina Yang (SNU: Seoul National University)H-Index: 8
#2Beomhee Kim (SNU: Seoul National University)
Last. Sang Woo Seo (SNU: Seoul National University)H-Index: 17
view all 5 authors...
With the increased attention on bio-based industry, demands for techniques that enable fast and effective strain improvement have been dramatically increased. Evolutionary engineering, which is less dependent on biological information, has been applied to strain improvement. Currently, synthetic biology has made great innovations in evolutionary engineering, particularly in the development of synthetic tools for phenotypic perturbation. Furthermore, discovering biological parts with regulatory r...
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