Match!
Mepur H. Ravindranath
Children's Hospital Los Angeles
AntibodyHuman leukocyte antigenImmunologyHLA-EMedicine
16Publications
3H-index
29Citations
What is this?
Publications 11
Newest
Source
#1Mepur H. Ravindranath (Children's Hospital Los Angeles)H-Index: 3
#2Edward J. Filippone (Thomas Jefferson University)H-Index: 8
Last. Shahab Asgharzadeh (SC: University of Southern California)H-Index: 29
view all 4 authors...
Cytotoxic NK/CD8+ T cells interact with MHC-I ligands on tumor cells through either activating or inhibiting receptors. One of the inhibitory receptors is CD94/NKG2A. The NK/CD8+ T cell cytotoxic c...
Source
#2Edward J. Filippone (Thomas Jefferson University)H-Index: 8
Last. Soldano Ferrone (Harvard University)H-Index: 91
view all 7 authors...
The accurate measurement of anti-HLA alloantibodies in transplant candidates is required for determining the degree of sensitization and for the listing of unacceptable antigens for organ allocation. Both the configuration of the HLA molecules coated on the beads and the nature of detection antibodies may impede assessment of the presence and strength of anti-HLA IgG- with the Luminex single-antigen-bead assay. Sera antibodies of the end-stage renal disease patients were compared using LIFECODES...
Source
#2Vadim JucaudH-Index: 6
Last. Paul I. TerasakiH-Index: 91
view all 7 authors...
Luminex multiplex immunoassays enable simultaneous monitoring of Abs against multiple Ags in autoimmune, inflammatory, and infectious diseases. The assays are used extensively to monitor anti-HLA Abs in transplant patients for donor organ selection, desensitization, and assessing the risk for graft rejection. To monitor IgG Abs, fluoresceinated IgG constant H chain–binding polyclonal F(ab′) 2 ( IgHPolyFab ) is used as the fluoresceinated secondary Ab (2nd-Ab), whereas IgG subclasses are monitore...
3 CitationsSource
#1Vadim JucaudH-Index: 6
Last. Paul I. TerasakiH-Index: 91
view all 3 authors...
BackgroundSingle antigen beads (SAB) are used for monitoring HLA antibodies in pretransplant and posttransplant patients despite the discrepancy between virtual and actual crossmatch results and transplant outcomes. This discrepancy can be attributed to the presence of conformational variants of HLA
8 CitationsSource
3 CitationsSource
#1Vadim JucaudH-Index: 6
Last. Paul I. TerasakiH-Index: 91
view all 3 authors...
4 CitationsSource
#2Vadim JucaudH-Index: 6
Last. Paul I. TerasakiH-Index: 91
view all 3 authors...
Source
#1D. ZhuH-Index: 2
Last. Paul I. TerasakiH-Index: 91
view all 6 authors...
Source
#2Paul I. TerasakiH-Index: 91
Last. Satoru KawakitaH-Index: 4
view all 3 authors...
Human major histocompatibility (MHC) class-I molecules consist of classical human leukocyte antigens (HLA) class-Ia, and nonclassical HLA class-Ib. HLA-Ia alleles are highly polymorphic, including HLA-A, with 2013 alleles and 1448 distinct proteins; HLA-B, with 2605 alleles and 1988 proteins; and HLA-Cw, with 1551 alleles and 1119 proteins. HLA-Ib alleles are less polymorphic, including HLA-E, with 11 alleles and three proteins; HLA-F, with 22 alleles and four proteins; and HLA-G, with 50 allele...
1 CitationsSource
12