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Yuta Saito
Hoshi University
PharmacokineticsDrug carrierConjugateIn vivoLiberation
1Publications
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#1Hiraku Onishi (Hoshi University)H-Index: 24
#2Yuta Saito (Hoshi University)H-Index: 1
Last. Yoshiharu Machida (Hoshi University)H-Index: 38
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Recently, many people have developed rheumatoid arthritis (RA), and prednisolone (PD) is often used for treatment; however, long use and a large dose of PD can cause toxic side effects. In this study, in order to enhance the therapeutic effects and to suppress the toxic side effects, the conjugate (GC–SP) was prepared by coupling between glycol-chitosan (GC) and succinyl-prednisolone (SP). The drug-release properties of GC–SP were examined and analyzed kinetically. The plasma concentration–time ...
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