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Michael Dennis Jensen
University of Rochester
69Publications
27H-index
8,526Citations
Publications 69
Newest
Published on May 1, 2018in Diabetes 7.27
Lisa S. Chow (UR: University of Rochester), Douglas G. Mashek (UR: University of Rochester)+ 4 AuthorsMichael Dennis Jensen27
Estimated H-index: 27
(UR: University of Rochester)
Intramyocellular lipid (IMCL) is generally associated with insulin resistance and lipotoxicity. However, the “athlete’s paradox” is well documented, where IMCL levels are similar between athletes and patients with type 2 diabetes despite discrepant levels of insulin sensitivity. Differences in muscle lipid metabolites between aerobically trained, lean, insulin-sensitive (LT) vs. sedentary, overweight/obese, insulin-resistant (OIR) individuals remain insufficiently characterized and may help to e...
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Published on May 1, 2018in Diabetes 7.27
Maria D. Hurtado (UR: University of Rochester), J.D. Adams (UR: University of Rochester)+ 5 AuthorsAdrian Vella39
Estimated H-index: 39
(UR: University of Rochester)
Elevations in both plasma free fatty acids (FFA) and glucose concentrations during fasting are associated with impaired β-cell function and predict progression from prediabetes to diabetes. Their interaction and subsequent effect on β-cell function as quantified by Disposition Index (DI) is unknown. We therefore measured total, saturated, mono-unsaturated and poly-unsaturated FFA concentrations using LC/MS in 120 nondiabetic subjects (across a range of fasting glucose p p = 0.59). On the other h...
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Published on May 1, 2018in Diabetes 7.27
Samyah Shadid (UR: University of Rochester), Michael Dennis Jensen27
Estimated H-index: 27
(UR: University of Rochester)
Background: Intramyocellular (im) triglycerides (TG) are increased in athletes, but also insulin resistant (IR) adults. To elucidate this discrepancy, we studied FFA storage in imTG and im oleyl-carnitine (OC) concentrations in IR humans pre and post 2 methods of insulin sensitization (IS) in the context of fitness (VO 2max ). Methods: 39 adults (BMI 28-36 kg/m 2 ) were given a diet/exercise program (DE; 11.7 ± 3.2 kg weight loss) or 30 mg/day pioglitazone (PI) for ∼19 weeks. Blood and muscle sa...
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Published on May 1, 2016in The Journal of Clinical Endocrinology and Metabolism 5.79
Sylvia Santosa13
Estimated H-index: 13
(UR: University of Rochester),
Sara L. Bonnes6
Estimated H-index: 6
(Mayo Clinic),
Michael Dennis Jensen27
Estimated H-index: 27
(UR: University of Rochester)
Context: Chronic sex steroid deficiency has effects on adipose fatty acid (FA) storage mechanisms and fat oxidation, but the chronology of events are not well understood. Objective: The objective of the study was to examine the acute effects of female sex steroid suppression on cellular mechanisms affecting abdominal and femoral subcutaneous adipose tissue FA storage. Design: This study had a randomized, longitudinal, parallel study design. Setting: The study was conducted at the Mayo Clinic Cli...
4 Citations Source Cite
Published on Jan 1, 2016
Jianrong Han10
Estimated H-index: 10
,
Gerri Waloga1
Estimated H-index: 1
+ 9 AuthorsTamara Tchkonia41
Estimated H-index: 41
Published on Jan 1, 2016
Susan A. Romanski7
Estimated H-index: 7
,
Rita M. Nelson7
Estimated H-index: 7
,
Michael Dennis Jensen27
Estimated H-index: 27
Published on Jan 1, 2016
Susan A. Romanski7
Estimated H-index: 7
,
Rita M. Nelson7
Estimated H-index: 7
,
Michael Dennis Jensen27
Estimated H-index: 27
Published on Feb 1, 2015in Diabetes Technology & Therapeutics 2.92
Sayeed Ikramuddin35
Estimated H-index: 35
,
Judith Korner25
Estimated H-index: 25
(Columbia University)
+ 16 AuthorsRobert W. Jeffery90
Estimated H-index: 90
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Published on Feb 1, 2015in The Journal of Physiology
Michael Dennis Jensen27
Estimated H-index: 27
(UR: University of Rochester)
The article by Blondin et al. (2015) in the current issue of The Journal of Physiology brings together and expands upon three adipose/muscle-related concepts that emphasize the importance of understanding physiology before jumping to conclusions when new findings are reported. First, the excitement following the reports of brown adipose tissue (BAT) in 2009 (Cypess et al. 2009; van Marken Lichtenbelt et al. 2009; Virtanen et al. 2009) has spawned a number of additional, enthusiastic reports of h...
11 Citations Source Cite
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