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Carlijn Brekelmans
Radboud University Nijmegen
Regulation of gene expressionGlycogen phosphorylaseOxidative stressGlycogenEpigenetics
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#1Human Riahi (Radboud University Nijmegen)H-Index: 2
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Stress responses are crucial processes that require activation of genetic programs that protect from the stressor. Stress responses are also energy consuming and can thus be deleterious to the organism. The mechanisms coordinating energy consumption during stress response in multicellular organisms are not well understood. Here, we show that loss of the epigenetic regulator G9a in Drosophila causes a shift in the transcriptional and metabolic responses to oxidative stress (OS) that leads to decr...
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