John D. Brannan
John Hunter Hospital
Physical therapyAsthmaMannitolBronchoconstrictionMedicine
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Publications 22
#1Jerry ZhouH-Index: 5
Last. John D. BrannanH-Index: 4
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Variability during spirometry can persist despite control of technical and personal factors. We postulate spirometry induces gastro-oesophageal reflux (GOR), which may cause variability and affect results of spirometry. Fifty-eight (58) subjects undergoing GOR investigation with oesophageal manometry and 24hr pH monitoring were recruited. Oesophageal dysmotility and GOR were assessed as part of clinical care. Subjects performed 2 sets of spirometry separated by a 10-minute rest period. The asses...
#1Hanna Nurmi (University of Eastern Finland)H-Index: 3
#2Anne M. LättiH-Index: 2
Last. Heikki O. Koskela (University of Eastern Finland)H-Index: 19
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Abstract Rationale Citric acid has been used as a cough provocation test for decades. However, the methods of administration have not been standardized. Inhaled mannitol is a novel cough provocation test, which has regulatory approval and can be performed utilizing a simple disposable inhaler in a standardized manner. Objective To compare the mannitol and citric acid cough provocation tests with respect to their ability to identify subjects with chronic cough and their tolerability. Methods Subj...
#1John D. BrannanH-Index: 4
#1John D. BrannanH-Index: 32
Last. Heikki O. KoskelaH-Index: 19
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1 CitationsSource
#1Clair LakeH-Index: 1
#2Keith WongH-Index: 25
Last. John D. BrannanH-Index: 32
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#1Peter A. B. Wark (University of Newcastle)H-Index: 41
#2Kim Cookson ('JHCH': John Hunter Hospital)H-Index: 1
Last. Douglas J. Dorahy (University of Newcastle)H-Index: 15
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Treatment of patients with Cystic Fibrosis homozygous for the Phe508del gene, with Lumacaftor /Ivacaftor (LUM/IVA) improves outcomes in patients with FEV1 > 40% predicted. We set out to observe the most sensitive clinical measure that would change with treatment in terms of exercise capacity or lung function in adults with severe lung disease as defined by an FEV1 < 40% predicted when clinically stable. 10 adults homozygous for the Phe508del received LUM/IVA. We assessed; six minute walk test (6...
#1Andrew Burgess ('JHCH': John Hunter Hospital)H-Index: 1
#2Ken Goon (Newcastle University)H-Index: 1
Last. Christopher GraingeH-Index: 15
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Background and objective: Publicly funded therapy for idiopathic pulmonary fibrosis (IPF) relies on percentage predicted values from pulmonary function testing, for example Australian patients must have a forced vital capacity ≥50% (%FVC), transfer factor of the lung for carbon monoxide ≥ 30% (%TLco) and forced expiratory volume in 1 s (FEV )/FVC ratio > 0.7. Despite defined cut-off values, no jurisdiction prescribes a reference equation for use; multiple equations exist. We hypothesized that ac...
1 CitationsSource
#1Marcelo Bezerra de Menezes (USP: University of São Paulo)H-Index: 4
#2Erica FerrazH-Index: 7
Last. Elcio Oliveira Vianna (USP: University of São Paulo)H-Index: 16
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ABSTRACTObjective: There is no standard definition of asthma for epidemiological purposes; most surveys use symptoms and bronchial hyperresponsiveness. Few studies tested mannitol challenge test (MCT) in occupational settings. We sought to determine efficacy and safety of MCT in detecting subjects with asthma symptoms in the workplace. Methods: In this cross-sectional study we recruited 908 workers in 2 universities; they underwent a respiratory questionnaire, spirometry, skin prick tests, and M...
2 CitationsSource
#1Hongyu Wang (St. Joseph's Healthcare Hamilton)H-Index: 2
#2Melanie Kjarsgaard (St. Joseph's Healthcare Hamilton)H-Index: 7
Last. Parameswaran Nair (St. Joseph's Healthcare Hamilton)H-Index: 33
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Sputum induction with hypertonic saline in obstructive airway diseases is generally safe. However, saline induces bronchoconstriction in some patients despite pre-medication with Salbutamol. Our objectives were to investigate the predictors of failure of Salbutamol to protect against saline-induced-bronchoconstriction in patients with asthma and COPD and to evaluate implications for asthma therapy. Retrospective survey on a database of 3565 patients with obstructive airway diseases who had sputu...
#1John D. Brannan ('JHCH': John Hunter Hospital)H-Index: 4
#2Celeste Porsbjerg (Bispebjerg Hospital)H-Index: 20
2 CitationsSource
#1Heikki O. Koskela (University of Eastern Finland)H-Index: 19
#2Clair Lake (USYD: University of Sydney)H-Index: 1
Last. John D. Brannan ('JHCH': John Hunter Hospital)H-Index: 4
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Mannitol challenge is a promising diagnostic test for cough hypersensitivity syndrome
2 CitationsSource