Maria A. Oquendo
University of Pennsylvania
Publications 497
#1Manesh Gopaldas (Columbia University)
#2Francesca Zanderigo (Columbia University)H-Index: 12
Last.M. Elizabeth Sublette (Columbia University)H-Index: 22
view all 11 authors...
Abstract BACKGROUND Serotonin transporter (5-HTT) binding and polyunsaturated fatty acids (PUFAs) are implicated in major depressive disorder (MDD). Links between the two systems in animal models have not been investigated in humans. METHODS Using positron emission tomography (PET) and [ 11 C]DASB, we studied relationships between 5-HTT binding potential and plasma levels of PUFAs docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), and arachidonic acid (AA) in medication-free MDD patients (...
#1A BrentDavid (University of Pittsburgh)H-Index: 97
#2Maria A. Oquendo (UPenn: University of Pennsylvania)H-Index: 76
Last.Charles F. Reynolds (University of Pittsburgh)H-Index: 107
view all 3 authors...
1 CitationsSource
#1Maria A. Oquendo (UPenn: University of Pennsylvania)H-Index: 76
#2Carol A. Bernstein (NYU: New York University)H-Index: 8
Last.Laurel Mayer (Columbia University)H-Index: 23
view all 3 authors...
3 CitationsSource
#1John G. Keilp (Columbia University)H-Index: 34
#2Kathy M. Corbera (Columbia University)H-Index: 3
Last.Brian A. Fallon (Columbia University)H-Index: 30
view all 6 authors...
3 CitationsSource
#1Allison V. MettsH-Index: 1
Last.J. John MannH-Index: 142
view all 10 authors...
#1Christian A. Webb (Harvard University)H-Index: 18
#2Madhukar H. TrivediH-Index: 91
Last.Diego A. Pizzagalli (Harvard University)H-Index: 60
view all 22 authors...
Background Major depressive disorder (MDD) is a highly heterogeneous condition in terms of symptom presentation and, likely, underlying pathophysiology. Accordingly, it is possible that only certain individuals with MDD are well-suited to antidepressants. A potentially fruitful approach to parsing this heterogeneity is to focus on promising endophenotypes of depression, such as neuroticism, anhedonia, and cognitive control deficits. Methods Within an 8-week multisite trial of sertraline v. place...
18 CitationsSource
#1Martin J. Lan (Columbia University)H-Index: 6
#2Mina M. Rizk (Columbia University)H-Index: 2
Last.J. John Mann (Columbia University)H-Index: 142
view all 9 authors...
2 CitationsSource
#1Martin J. LanH-Index: 6
Last.J. John MannH-Index: 142
view all 9 authors...
#1J. John MannH-Index: 142
#2Jeffrey M. MillerH-Index: 14
Last.M. Elizabeth SubletteH-Index: 22
view all 8 authors...