Andrea Vannini
University of Bologna
PromoterVirologyGeneticsOncolytic virusBiology
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Publications 16
#1Laura MenottiH-Index: 17
#2Valerio LeoniH-Index: 8
view all 8 authors...
#1Andrea VanniniH-Index: 7
#2Biljana PetrovicH-Index: 5
Last. Tatiana GianniH-Index: 15
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#1Andrea Vannini (UNIBO: University of Bologna)H-Index: 7
#2Valerio Leoni (UNIBO: University of Bologna)H-Index: 8
Last. Tatiana Gianni (UNIBO: University of Bologna)H-Index: 15
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Tumors utilize a number of effective strategies, including the programmed death 1/PD ligand 1 (PD-1/PD-L1) axis, to evade immune-mediated control of their growth. PD-L1 expression is mainly induced by IFN receptor signaling or constitutively induced. Integrins are an abundantly expressed class of proteins which play multiple deleterious roles in cancer and exert proangiogenic and prosurvival activities. We asked whether αvβ3-integrin positively regulates PD-L1 expression and the anticancer immun...
2 CitationsSource
#1Francisco J. Ruiz Gómez (UCO: University of Córdoba (Spain))H-Index: 2
#2Rafael María Navarro Cerrillo (UCO: University of Córdoba (Spain))H-Index: 17
Last. Carmen Morales-Rodríguez (TUM: Technische Universität München)H-Index: 4
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Forest decline is nowadays a major challenge for ecosystem sustainability. Dehesas, which consists of savannah-like mediterranean ecosystems, are threatened by the holm oak decline in the south-west of Iberian Peninsula. Phytophthora cinnamomi is considered the main agent of holm oak root rot, but little is known about the relationship between diversity of soilborne microbial community and the decline syndrome of holm oak. It would be hypothesized that the changes in the structure and functional...
4 CitationsSource
#1Simona Pepe (UNIBO: University of Bologna)H-Index: 2
#2Eva Pinatel (National Research Council)H-Index: 7
Last. Davide Roncarati (UNIBO: University of Bologna)H-Index: 12
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The ability of pathogens to perceive environmental conditions and modulate gene expression accordingly is a crucial feature for bacterial survival. In this respect, the heat-shock response, a universal cellular response, allows cells to adapt to hostile environmental conditions and to survive during stress. In the major human pathogen Helicobacter pylori the expression of chaperone-encoding operons is under control of two auto-regulated transcriptional repressors, HrcA and HspR, with the latter ...
4 CitationsSource
#1Valerio Leoni (UNIBO: University of Bologna)H-Index: 8
#2Andrea Vannini (UNIBO: University of Bologna)H-Index: 7
Last. Gabriella Campadelli-Fiume (UNIBO: University of Bologna)H-Index: 41
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Oncolytic herpes simplex viruses (oHSVs) showed efficacy in clinical trials and practice. Most of them gain cancer-specificity from deletions/mutations in genes that counteract the host response, and grow selectively in cancer cells defective in anti-viral response. Because of the deletions/mutations, they are frequently attenuated or over-attenuated. We developed next-generation oHSVs, which carry no deletion/mutation, gain cancer-specificity from specific retargeting to tumor cell receptors—e....
10 CitationsSource
#1Biljana PetrovicH-Index: 5
#2Valerio LeoniH-Index: 8
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3 CitationsSource
#1Andrea VanniniH-Index: 7
#2Eva PinatelH-Index: 7
Last. Alberto DanielliH-Index: 8
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Comprehensive mapping of the Helicobacter pylori NikR regulon provides new insights in bacterial nickel responses
7 CitationsSource
#1Simone PelliciariH-Index: 4
#2Eva PinatelH-Index: 7
Last. Davide RoncaratiH-Index: 12
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Insight into the essential role of the Helicobacter pylori HP1043 orphan response regulator: genome-wide identification and characterization of the DNA-binding sites
8 CitationsSource