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Momoko Suzuki
Meiji Pharmaceutical University
Darzens reactionOrganic chemistryChemistryTotal synthesisStereochemistry
4Publications
1H-index
3Citations
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Publications 5
Newest
#1Kenichi Kobayashi (Meiji Pharmaceutical University)H-Index: 5
#2Kosaku Tanaka (Meiji Pharmaceutical University)H-Index: 3
Last. Hiroshi Kogen (Meiji Pharmaceutical University)H-Index: 18
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A catalytic asymmetric intramolecular Darzens reaction of 2-halomalonate derivatives was developed for the enantioselective preparation of chiral building blocks for epoxide-containing natural prod...
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#1Momoko Suzuki (Meiji Pharmaceutical University)H-Index: 1
#2Shougo Hashimoto (Meiji Pharmaceutical University)
Last. Kenichi Kobayashi (Meiji Pharmaceutical University)H-Index: 5
view all 5 authors...
Epothilone D, a microtubule-stabilizing macrolide, is an attractive synthetic target molecule as a potential anti-cancer drug candidate. As part of our ongoing synthetic studies of this natural pro...
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#1Kosaku Tanaka (Meiji Pharmaceutical University)H-Index: 3
#2Yusuke Honma (Meiji Pharmaceutical University)H-Index: 1
Last. Hiroshi Kogen (Meiji Pharmaceutical University)H-Index: 18
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Abstract The relative and absolute configurations of L-755,807 were established through total synthesis. All four possible stereoisomers were prepared via a convergent synthetic strategy, including a novel diastereoselective Darzens reaction of an α-alkoxy aldehyde with di- tert -butyl bromomalonate, an E -selective Horner–Wadsworth–Emmons reaction, and late-stage coupling of the ring and side-chain segments. Additionally, biological evaluation of the synthesized compounds revealed their potent ...
3 CitationsSource
#1Hiroshi KogenH-Index: 18
#2Kenichi KobayashiH-Index: 5
Last. Momoko SuzukiH-Index: 1
view all 8 authors...
Source
#1Kenichi KobayashiH-Index: 5
#2Hiroshi KogenH-Index: 18
Last. Momoko SuzukiH-Index: 1
view all 5 authors...
Source
1