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Nguyen Viet Phong
Vietnam Academy of Science and Technology
4Publications
1H-index
1Citations
Publications 4
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#1Le Ba Vinh (VAST: Vietnam Academy of Science and Technology)H-Index: 2
#2Hyun-Jae Jang (Korea Research Institute of Bioscience and Biotechnology)H-Index: 5
Last.Seo Young Yang (CNU: Chungnam National University)H-Index: 12
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Abstract Chromatography of the ethanol extract of the medicinal fruit Stauntonia hexaphylla resulted in the purification of 26 compounds ( 1 − 26 ), including two undescribed triterpene saponins 1 and 2 (hexaphylosides A and B). Their structures were confirmed by spectroscopic data, including IR, HR QTOF MS, 1 H, 13 C-NMR, COSY, HMQC, HMBC, and TOCSY, and HPLC sugar analysis after acid hydrolysis. The anti-inflammatory effects of the high-purity constituents ( 1 – 26 ) on lipopolysaccharide (LPS...
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#1Le Ba Vinh (VAST: Vietnam Academy of Science and Technology)H-Index: 2
#2Hyun-Jae Jang (Korea Research Institute of Bioscience and Biotechnology)H-Index: 5
Last.Seo Young Yang (CNU: Chungnam National University)H-Index: 12
view all 8 authors...
Abstract Using various chromatographic techniques, 23 triterpene saponins ( 1–23 ) were isolated from an ethanol extract of Stauntonia hexaphylla , including two new compounds ( 12 and 15 ). Their chemical structures were established by comprehensive spectroscopic methods such as 1D- and 2D-NMR, and HR-ESI-MS, and chemical reactions. The anti-inflammatory activities of the isolated saponins were determined using the nitric oxide (NO) assay. Compound 13 exhibited the greatest inhibitory effect (I...
1 CitationsSource
#1Pham Thi Mai Huong (VAST: Vietnam Academy of Science and Technology)H-Index: 3
#2Nguyen Viet Phong (VAST: Vietnam Academy of Science and Technology)H-Index: 1
Last.Chau Van Minh (VAST: Vietnam Academy of Science and Technology)H-Index: 23
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Using various chromatographic separations, four steroids including one new C20 steroid namely dendrodoristerol (1), were isolated from the Vietnamese nudibranch mollusk Dendrodoris fumata. The structure elucidation was confirmed by combination of spectroscopic experiments including 1D and 2D NMR, HR QTOF MS, and CD. Compound 1 was found to exhibit significant in vitro cytotoxic activity against six human cancer cell lines as HL-60, KB, LU-1, MCF-7, LNCaP, and HepG2. In addition, 1 induced HL-60 ...
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#1Nguyen Van Thanh (VAST: Vietnam Academy of Science and Technology)H-Index: 8
#2Nguyen Phuong Thao (VAST: Vietnam Academy of Science and Technology)H-Index: 17
Last.Chau Van Minh (VAST: Vietnam Academy of Science and Technology)H-Index: 23
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A new [7.7]paracyclophane (1), together with eight known compounds (2-9), were isolated from a MeOH extract of the sea snail Planaxis sulcatus (Born, 1780). Their structures were elucidated by HR-ESI-MS and NMR techniques as well as comparison with those reported in literatures. The absolute configuration of metabolite 1 was determined using ECD spectroscopy. Among nine compounds, 1 exhibited significant cytotoxicity toward all eight cancer cells tested with IC50 values between 1.81 and 3.80 µg/...
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