Yuhan Shi
Chinese Academy of Sciences
Publications 3
#1Sanlan Li (CAS: Chinese Academy of Sciences)H-Index: 2
#2Yuhan Shi (CAS: Chinese Academy of Sciences)H-Index: 1
Last.Leping Cheng (CAS: Chinese Academy of Sciences)H-Index: 18
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Summary Dysfunction of noradrenergic (NA) neurons is associated with a number of neuronal disorders. Diverse neuronal subtypes can be generated by direct reprogramming. However, it is still unknown how to convert non-neuronal cells into NA neurons. Here, we show that seven transcription factors (TFs) (Ascl1, Phox2b, AP-2α, Gata3, Hand2, Nurr1, and Phox2a) are able to convert astrocytes and fibroblasts into induced NA (iNA) neurons. These iNA neurons express the genes required for the biosynthesi...
#1Xishan Lu (CAS: Chinese Academy of Sciences)H-Index: 9
#2Haixia Xiao (CAS: Chinese Academy of Sciences)H-Index: 20
Last.G.F. GaoH-Index: 1
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Summary Yellow fever virus (YFV), a deadly human pathogen, is the prototype of the genus Flavivirus. Recently, YFV re-emerged in Africa and Brazil, leading to hundreds of deaths, with some cases imported to China. Prophylactic or therapeutic countermeasures are urgently needed. Previously, several human monoclonal antibodies against YFV were screened out by phage display. Here, we find that one of them, 5A, exhibits high neutralizing potency and good protection. Crystallographic analysis of the ...
2 CitationsSource
#1Sue HanH-Index: 1
Last.Leping ChengH-Index: 18
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