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Xiang-Chong Wang
Hebei University
Publications 1
Published on Feb 1, 2019in Vascular Pharmacology 3.33
Wen-Tao Sun (TEDA International Cardiovascular Hospital), Xiang-Chong Wang (Hebei University)+ 3 AuthorsQin Yang1
Estimated H-index: 1
(TEDA International Cardiovascular Hospital)
Abstract Objectives We recently reported the involvement of ER stress-mediated BK Ca channel inhibition in homocysteine-induced coronary dilator dysfunction. In another study, we demonstrated that tetramethylpyrazine (TMP), an active ingredient of the Chinese herb Chuanxiong, possesses potent anti-ER stress capacity. The present study investigated whether TMP protects BK Ca channels from homocysteine-induced inhibition and whether suppression of ER stress is a mechanism contributing to the prote...