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El-Habib Dakir
University of Bradford
2Publications
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#1El-Habib Dakir (University of Bradford)H-Index: 1
#2Adam Pickard ('QUB': Queen's University Belfast)H-Index: 11
Last.Mohamed El-Tanani (University of Bradford)H-Index: 18
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Pimozide, an antipsychotic drug of the diphenylbutylpiperidine class, has been shown to suppress cell growth of breast cancer cells in vitro. In this study we further explore the inhibitory effects of this molecule in cancer cells. We found that Pimozide inhibited cell proliferation in a dose- and time-dependent manner in MDA-MB-231 breast cancer cells and A549 lung cancer cells. Furthermore, we found that Pimozide also promoted apoptosis as demonstrated by cell cycle arrest and induction of dou...
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