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Zee Upton
Agency for Science, Technology and Research
11Publications
1H-index
2Citations
Publications 11
Newest
Published on Sep 1, 2019in Chemico-Biological Interactions 3.41
Chen Fan1
Estimated H-index: 1
(Agency for Science, Technology and Research),
Lay Keng Priscilla Lim (Agency for Science, Technology and Research)+ 3 AuthorsDavid Leavesley (Agency for Science, Technology and Research)
Abstract Pathological scarring is an intractable problem for both patients and clinicians. A major obstacle for the development of scar remediation therapies is the paucity of suitable in vivo and in vitro models. The “Scar-in-a-jar” model was previously established by our colleagues based on the principle of “Macromolecular crowding”. This has been demonstrated to be an extracellular matrix-rich in vitro model offering a novel tool for studies related to the extracellular matrix. In the study r...
Published on May 1, 2018in Journal of Investigative Dermatology 6.29
M. Andrade (Manipal University), Kapaettu Satyamoorthy33
Estimated H-index: 33
(Manipal University)
+ 1 AuthorsD. Van Lonkhuyzen (QUT: Queensland University of Technology)
Published on Apr 1, 2018in International Wound Journal 2.38
Zee Upton1
Estimated H-index: 1
(Agency for Science, Technology and Research),
Melissa L. Fernandez1
Estimated H-index: 1
(Agency for Science, Technology and Research)
Published on Jan 1, 2018in Pharmaceutical Biology 2.49
Chen Fan1
Estimated H-index: 1
(Agency for Science, Technology and Research),
Xufang Zhang1
Estimated H-index: 1
(SYSU: Sun Yat-sen University),
Zee Upton1
Estimated H-index: 1
(Agency for Science, Technology and Research)
AbstractContext: Shikonin (SHI), an active component extracted from Radix Arnebiae, has been reported to possess anti-inflammatory properties in various cells. However, its effect on lipopolysaccharide (LPS)-stimulated human periodontal ligament cells (hPDLCs) is unknown.Objective: To investigate the effects of SHI on the expression of inflammatory related cytokines in LPS-stimulated hPDLCs.Materials and methods: The effects of SHI (0.125, 0.25, 0.5, 1, and 2 μg/mL) on hPDLCs proliferation for 1...
Published on Jan 1, 2015
Keith Gordon Harding55
Estimated H-index: 55
,
Pat Aldons1
Estimated H-index: 1
+ 9 AuthorsEmily Lynam5
Estimated H-index: 5
Hard-to-heal leg ulcers are a major cause of morbidity in the elderly population. Despite improvements in wound care, some wounds will not heal and they present a significant challenge for patients and health care providers. A multi-centre cohort study was conducted to evaluate the effectiveness and safety of a synthetic, extracellular matrix protein as an adjunct to standard care in the treatment of hard-to-heal venous or mixed leg ulcers. Primary effectiveness criteria were (i) reduction in wo...
Published on Jan 1, 2012
Dario Stupar2
Estimated H-index: 2
,
Tony J. Parker6
Estimated H-index: 6
+ 2 AuthorsMelissa L. Fernandez1
Estimated H-index: 1
Published on Jan 1, 2010in Growth Hormone & Igf Research 2.17
Zee Upton1
Estimated H-index: 1
,
Gary K. Shooter8
Estimated H-index: 8
+ 6 AuthorsMichael Stacey25
Estimated H-index: 25
Published on Jan 1, 2010in Growth Hormone & Igf Research 2.17
Zee Upton1
Estimated H-index: 1
,
Abhishek S. Kashyap5
Estimated H-index: 5
+ 3 AuthorsDavid I. Leavesley28
Estimated H-index: 28
anticancer potential. Fenofibrate is a potent agonist of peroxisome proliferator activated receptor alpha (PPARa) that can switch energy metabolism from glycolysis to fatty acid b-oxidation, and has low systemic toxicity. Fenofibrate also attenuates IGF-I-mediated cellular responses, which could be relevant in the process of glioblastoma cell dispersal. Methods: The effects of fenofibrate on glioma cell motility, IGF-I receptor (IGF-IR) signaling, PPARa activity, reactive oxygen species (ROS) me...
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