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Eleni Pilitsi
Beth Israel Deaconess Medical Center
EndocrinologyLeptinWeight lossDiabetes mellitusBiology
5Publications
1H-index
16Citations
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Publications 5
Newest
#1Nikolaos Perakakis (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 9
#2Alexander Kokkinos (UoA: National and Kapodistrian University of Athens)H-Index: 15
Last. Christos S. Mantzoros (Harvard University)H-Index: 106
view all 9 authors...
Abstract Aims Bariatric surgery leads to profound and sustainable weight loss. Gastrointestinal hormones are involved in energy and glucose homeostasis, thus postoperative changes of their circulating levels may be mediating future weight loss. To investigate how the circulating concentrations of gastrointestinal hormones change in response to the most common types of bariatric operation and whether these changes can predict future weight loss. Materials and Methods We measured circulating GLP-1...
3 CitationsSource
#1Eleni Pilitsi (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 1
#2Natia Peradze (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 2
Last. Christos S. Mantzoros (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 106
view all 4 authors...
Abstract Objective It remains unclear whether food deprivation induces changes in components of the GH/IGF-1/IGFBPs axis and if yes, which ones are mediated by leptin, an adipocyte secreted hormone regulating neuroendocrine response to energy deprivation in animals and humans. We aimed to investigate components of the axis that have not been studied to date, i.e. IGF-binding proteins (IGFBPs) and related proteases (total and intact IGFBP 3 and IGFBP 4, total IGFBP 5, PAPPA, PAPPA2 and Stanniocal...
Source
#1Olivia M. Farr (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 20
#2Eleni Pilitsi (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 1
Last. Christos S. Mantzoros (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 106
view all 3 authors...
Abstract Incretins have risen to the forefront of therapies for obesity and related metabolic complications, primarily because of their efficacy and relatively few side effects. Importantly, their efficacy in altering energy balance and decreasing body weight is apparently through actions in the central nervous system (CNS); the latter may have implications beyond obesity per se, i.e. in other disease states associated with obesity including CNS-related disorders. Here, we first describe the rol...
Source
#1Pavlina Chrysafi (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 1
#2Natia Peradze (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 2
Last. Christos S. Mantzoros (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 106
view all 6 authors...
Source
#1Eleni Pilitsi (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 1
#2Olivia M. Farr (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 20
Last. Christos S. Mantzoros (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 106
view all 7 authors...
Abstract Obesity is a chronic disease with a continuously rising prevalence that currently affects more than half a billion people worldwide. Energy balance and appetite are highly regulated via central and peripheral mechanisms, and weight loss triggers a homeostatic response leading to weight regain. Lifestyle and behavioral modifications are the cornerstones of obesity management; however, they often fail to achieve or sustain long-term weight loss. Pharmacotherapy added onto lifestyle modifi...
16 CitationsSource
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