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Yuying Liu
University of Texas Health Science Center at Houston
ImmunologyLactobacillus reuteriNecrotizing enterocolitisDiabetes mellitusMedicine
54Publications
13H-index
747Citations
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Publications 54
Newest
#1Yuying LiuH-Index: 13
#2Xiangjun Tian (University of Texas MD Anderson Cancer Center)H-Index: 1
Last. Jon Marc Rhoads (University of Texas Health Science Center at Houston)H-Index: 7
view all 14 authors...
Early administration of Lactobacillus reuteri DSM 17938 (LR) prevents necrotizing enterocolitis and inhibits Treg-deficiency-associated autoimmunity in mice. In humans, LR reduces crying time in br...
2 CitationsSource
#1Baokun He (SJTU: Shanghai Jiao Tong University)H-Index: 7
#1Baokun He (SJTU: Shanghai Jiao Tong University)
Last. J. Marc Rhoads (University of Texas Health Science Center at Houston)H-Index: 27
view all 9 authors...
Regulatory T cell (Treg) deficiency leads to IPEX syndrome, a lethal autoimmune disease, in Human and mice. Dysbiosis of the gut microbiota in Treg-deficient scurfy (SF) mice has been described, but to date, the role of the gut microbiota remains to be determined. To examine how antibiotic-modified microbiota can inhibit Treg deficiency-induced lethal inflammation in SF mice, Treg-deficient SF mice were treated with three different antibiotics. Different antibiotics resulted in distinct microbio...
Source
#1Tu T. MaiH-Index: 1
#2Dat Q. TranH-Index: 34
Last. Yuying LiuH-Index: 13
view all 5 authors...
Human breast milk (HBM) may have beneficial effects on Lactobacillus reuteri DSM 17938 (LR 17938) -mediated immunomodulation. We aimed to determine the effects of HBM on proliferation of LR 17938 in vitro and its associated proteins and metabolites in culture, in order to provide mechanistic insights into the health benefits of LR 17938. LR 17938 was cultured anaerobically in MRS bacterial culture media, HBM (from 6 mothers), and 2 types of cow-milk formula. The colony-forming unit (CFU) was cal...
Source
#1Yuying LiuH-Index: 13
#2Thomas K. HoangH-Index: 4
Last. J. Marc RhoadsH-Index: 27
view all 11 authors...
Source
#1Yuying LiuH-Index: 13
#2Xiangjun TianH-Index: 12
Last. J. Marc RhoadsH-Index: 27
view all 11 authors...
Source
#1Tu T. MaiH-Index: 1
#2Yuying LiuH-Index: 13
Last. J. Marc RhoadsH-Index: 27
view all 7 authors...
Source
#1Baokun He (University of Texas Health Science Center at Houston)H-Index: 7
#2Thomas K. Hoang (University of Texas Health Science Center at Houston)H-Index: 4
Last. Yuying Liu (University of Texas Health Science Center at Houston)H-Index: 13
view all 14 authors...
The gut microbiome plays an important role in immune function and has been implicated in multiple sclerosis (MS). However, how and if the modulation of microbiota can prevent or treat MS remain largely unknown. In this study, we showed that probiotic Lactobacillus reuteri DSM 17938 (L. reuteri) ameliorated the development of murine experimental autoimmune encephalomyelitis (EAE), a widely used animal model of MS, a model which is primarily mediated by TH17 and TH1 cells. We discovered that L. re...
1 CitationsSource
#1Lindsay Marie Moye (University of Texas at Austin)
#2Yuying Liu (University of Texas at Austin)H-Index: 13
Last. Jon Marc Rhoads (University of Texas at Austin)H-Index: 7
view all 5 authors...
Background: Eosinophilic esophagitis (EoE) is a disorder of the esophagus that has become increasingly recognized in children. Because these children undergo multiple endoscopies, discovering a noninvasive biomarker of disease activity is highly desirable. The aim of this study was to use targeted plasma metabolomics to identify potential biomarker candidates for EoE in a discovery phase. Methods: A prospective, single-center clinical trial was performed on 24 children ages 2-18 years with and w...
Source
#1Thomas K. HoangH-Index: 4
#2Jasmin FreebornH-Index: 1
Last. Yuying LiuH-Index: 13
view all 10 authors...
Background and objective: Breast milk has many growth-promoting and immune-active components, including transforming growth factor-β, lactoferrin, lysozyme, immunoglobulin A, and prebiotics such as the human milk oligosaccharides. Treatment with Lactobacillus reuteri DSM 17938 (LR), a probiotic with immunomodulatory functions, significantly increases regulatory T cells (Tregs) in the intestinal mucosa of newborn suckling rats. In humans, treatment with LR of infants with colic reduces crying opt...
Source
#1J. Marc Rhoads (University of Texas Health Science Center at Houston)H-Index: 27
#2Jeffrey J. Collins (BCM: Baylor College of Medicine)H-Index: 132
Last. Yuying Liu (University of Texas Health Science Center at Houston)H-Index: 13
view all 11 authors...
Objective To dissect potential confounding effects of breast milk and formula feeding on crying + fussing, fecal calprotectin, and gut microbiota in babies with colic. We hypothesized that infant colic is associated with gut inflammation linked to intestinal dysbiosis. Study design A nested case-control design of 3 of our studies was used to analyze clinical and laboratory data at presentation, comparing babies with colic with controls. All investigators other than the biostatistician were blind...
10 CitationsSource
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