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Chengyu Wang
Guangzhou Medical University
PsychologyAntidepressantMajor depressive disorderKetamineAnesthesia
16Publications
7H-index
72Citations
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Publications 16
Newest
#1Xiaofeng Lan (Guangzhou Medical University)H-Index: 1
#2Yanling Zhou (Guangzhou Medical University)H-Index: 7
Last. Yuping Ning (Southern Medical University)H-Index: 1
view all 10 authors...
Abstract Background Suicidal ideation (SI) is common in patients with major depressive disorder (MDD) and often related to cognitive deficits. Limited longitudinal study has shown that cognitive improvement is associated with reduced SI. However, the comparatively study in Chinese depressed patients is still absent. The objective of this study was to explore the specific cognitive deficits in Chinese MDD with SI and investigate the relationship between changes in cognition and change in SI acros...
Source
#1Wei Zheng (Guangzhou Medical University)H-Index: 127
#2Yanling Zhou (Guangzhou Medical University)H-Index: 7
Last. Yuping Ning (Southern Medical University)H-Index: 1
view all 8 authors...
Abstract Objectives Ketamine has shown rapid antidepressant effects in depressed patients. However, the antidepressant and antisuicidal effects of repeated ketamine infusions in patients with treatment-resistant bipolar depression (TRBD) are not known. Methods TRBD patients received six intravenous infusions of 0.5 mg/kg ketamine over 40 min on a Monday–Wednesday–Friday schedule during a 12-day period followed by a 2-week follow-up period. Depressive symptoms were measured by the Montgomery-Asbe...
Source
#1Weijian Liu (Southern Medical University)H-Index: 1
#2Yanling Zhou (Guangzhou Medical University)H-Index: 7
Last. Yuping Ning (Southern Medical University)H-Index: 1
view all 9 authors...
Source
#1Weijian Liu (Southern Medical University)H-Index: 1
#2Yanling Zhou (Guangzhou Medical University)H-Index: 7
Last. Mingding Li (ZJU: Zhejiang University)H-Index: 3
view all 11 authors...
Source
#1Weijian Liu (Southern Medical University)H-Index: 1
#1Weijian Liu (Guangzhou Medical University)H-Index: 6
Last. Mingding Li (ZJU: Zhejiang University)H-Index: 3
view all 11 authors...
Abstract Objective Ketamine has been demonstrated to have robust and rapid antidepressant effects, and few studies have focused on the relationship between insomnia and the efficacy of ketamine. The objective of this study was to examine whether baseline insomnia predicted the antidepressant efficacy of repeated intravenous ketamine infusions for unipolar and bipolar depression. Method Patients with high insomnia (n = 64) or low insomnia (n = 68) received six intravenous infusions of ketamine (0...
Source
#1Yanni Zhan (Southern Medical University)H-Index: 1
#2Bin Zhang (Guangzhou Medical University)H-Index: 5
Last. Martin Walter (University of Tübingen)H-Index: 41
view all 13 authors...
Source
#1Yanling Zhou (Guangzhou Medical University)H-Index: 7
#2Weijian Liu (Guangzhou Medical University)H-Index: 6
Last. Yuping Ning (Guangzhou Medical University)H-Index: 15
view all 9 authors...
Abstract Background Ketamine has rapid-acting antidepressant and antisuicidal properties, while a proportion of patients do not adequately achieve a complete response to ketamine. Our aim was to explore the applicability of using clinical factors and serum tryptophan (TRP) metabolites to predict the response to six doses of ketamine for depression with suicidal ideation. Methods Seventy-three depressed patients with suicidal ideation received a thrice-weekly infusion regimen of subanaesthetic do...
Source
#1Weijian Liu (Guangzhou Medical University)H-Index: 6
#2Yanling Zhou (Guangzhou Medical University)H-Index: 7
Last. Yuping Ning (Guangzhou Medical University)H-Index: 15
view all 10 authors...
Abstract Background Recent studies have suggested that neurocognition is changed after repeated infusions of ketamine in patients with treatment-resistant depression (TRD). The objective of this study was to investigate whether differences existed in the neurocognitive effect of six ketamine infusions in patients with anxious and nonanxious TRD and to determine the association between baseline neurocognition and changes in symptoms after the infusions. Method Patients with anxious (n = 30) and n...
2 CitationsSource
#1Yanni Zhan (Southern Medical University)H-Index: 6
#2Bin Zhang (Guangzhou Medical University)H-Index: 5
Last. Yuping Ning (Southern Medical University)H-Index: 1
view all 13 authors...
Abstract Background Suicide is a tremendous public health crisis and is demanded urgent intervention. Previous studies found that ketamine intervention could rapidly reduce suicidal ideation in depression. However, the comparatively study in Chinese population remains absence. The current study aims to assess the anti-suicidal efficacy of repeated ketamine infusions for Chinese depressed suicidal patients, especially distinguish between low suicidal ideation (SI) group and high SI group. Methods...
Source
#1Wei Zheng (Guangzhou Medical University)H-Index: 127
#2Yanling Zhou (Guangzhou Medical University)H-Index: 7
Last. Yuping Ning (Guangzhou Medical University)H-Index: 15
view all 9 authors...
Abstract Objective Ketamine has demonstrated a rapid antidepressant and antisuicidal effect in patients with major depressive disorder (MDD), but the neurocognitive effects of ketamine are relatively unknown. This study aims to examine the neurocognitive effects of six ketamine infusions and the association of baseline neurocognitive function and the change in severity of depressive symptoms after the last infusions. Methods Sixty-four patients with MDD completed six intravenous infusions of ket...
2 CitationsSource
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