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Donald G. Gilbert
Indiana University Bloomington
14Publications
12H-index
1,299Citations
Publications 14
Newest
#1Alfredo Rago (University of Birmingham)H-Index: 4
#2Donald G. Gilbert (IU: Indiana University)H-Index: 12
Last.John K. Colbourne (University of Birmingham)H-Index: 42
view all 8 authors...
Background Nasonia vitripennis is an emerging insect model system with haplodiploid genetics. It holds a key position within the insect phylogeny for comparative, evolutionary and behavioral genetic studies. The draft genomes for N. vitripennis and two sibling species were published in 2010, yet a considerable amount of transcriptiome data have since been produced thereby enabling improvements to the original (OGS1.2) annotated gene set. We describe and apply the EvidentialGene method used to pr...
#1Rebecca P. Duncan (UM: University of Miami)H-Index: 9
#2Filip Husník (Sewanee: The University of the South)H-Index: 8
Last.Alexandra Wilson (UM: University of Miami)H-Index: 18
view all 7 authors...
Symbiosis is well known to influence bacterial symbiont genome evolution and has recently been shown to shape eukaryotic host genomes. Intriguing patterns of host genome evolution, including remarkable numbers of gene duplications, have been observed in the pea aphid, a sap-feeding insect that relies on a bacterial endosymbiont for amino acid provisioning. Previously, we proposed that gene duplication has been important for the evolution of symbiosis based on aphid-specific gene duplication in a...
#1John H. Werren (UR: University of Rochester)H-Index: 70
#2Stephen J. Richards (BCM: Baylor College of Medicine)H-Index: 14
Last.Cornelis J. P. Grimmelikhuijzen (UCPH: University of Copenhagen)H-Index: 57
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We report here genome sequences and comparative analyses of three closely related parasitoid wasps: Nasonia vitripennis, N. giraulti, and N. longicornis. Parasitoids are important regulators of arthropod populations, including major agricultural pests and disease vectors, and Nasonia is an emerging genetic model, particularly for evolutionary and developmental genetics. Key findings include the identification of a functional DNA methylation tool kit; hymenopteran-specific genes including diverse...
#1Alexander StarkH-Index: 57
#2Michael F. LinH-Index: 21
Last.Ameya N. DeorasH-Index: 2
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Sequencing of multiple related species followed by comparative genomics analysis constitutes a powerful approach for the systematic understanding of any genome. Here, we use the genomes of 12 Drosophila species for the de novo discovery of functional elements in the fly. Each type of functional element shows characteristic patterns of change, or 'evolutionary signatures', dictated by its precise selective constraints. Such signatures enable recognition of new protein-coding genes and exons, spur...
The Drosophila species comparative genome database DroSpeGe (http://insects.eugenes.org/ DroSpeGe/) provides genome researchers with rapid, usable access to 12 new and old Drosophila genomes, since its inception in 2004. Scientists can use, with minimal computing expertise, the wealth of new genome information for developing new insights into insect evolution. New genome assemblies provided by several sequencing centers have been annotated with known model organism gene homologies and gene predi...
#1Donald G. Gilbert (IU: Indiana University Bloomington)H-Index: 12
euGenes is a genome information system and database that provides a common summary of eukaryote genes and genomes, at http://iubio.bio.indiana.edu/eugenes/. Seven popular genomes are included: human, mouse, fruitfly, Caenorhabditis elegans worm, Saccharomyces yeast, Arabidopsis mustard weed and zebrafish, with more planned. This information, automatically extracted and updated from several source databases, offers features not readily available through other genome databases to bioscientists loo...
#1Donald G. Gilbert (IU: Indiana University Bloomington)H-Index: 12
#2Rollin C. Richmond (IU: Indiana University Bloomington)H-Index: 24
Last.Kathy B. Sheehan (IU: Indiana University Bloomington)H-Index: 20
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Esterase 6 (EST 6) inDrosophila melanogaster is a male reproductive enzyme transferred to females as a component of the seminal fluid [Richmond, R. C., Gilbert, D. G., Sheehan, K. B., Gromko, M. H., and Butterworth, F. W. (1980).Science207:1483–1485]. Here we report investigations into the relation between EST 6 and remating by females. EST 6 activity in a strain selected for decreased time to remating is increased over control levels. Inseminated females remated to males carrying null or active...
#1Donald G. Gilbert (IU: Indiana University Bloomington)H-Index: 12
Abstract The period of initial sperm storage and use by Drosophila melanogaster females is examined for effects of the seminal fluid enzyme esterase 6. Females mated to males differing in their level of esterase 6 activity were dissected from 5 min to 50 hr after the start of copulation and numbers of sperm contained in the uterus, ventral receptacle and paired spermathecae were counted. Of the 4000–6000 sperm transferred at copulation, about 700 are stored in the receptacle by 4 hr post mating ...
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