Branding/Logomark minus Citation Combined Shape Icon/Bookmark-empty Icon/Copy Icon/Collection Icon/Close Copy 7 no author result Created with Sketch. Icon/Back Created with Sketch. Match!
Jay I. Lakkis
University of Maryland Medical System
4Publications
2H-index
5Citations
Publications 4
Newest
Published on Jan 1, 2019
Jay I. Lakkis2
Estimated H-index: 2
(University of Maryland Medical System),
Matthew R. Weir28
Estimated H-index: 28
(University of Maryland Medical System)
This chapter provides a clinical perspective on how the kidney can be used as a sentinel for cardiovascular disease (CVD) burden and, perhaps, as a means of measuring therapeutic success for the treatment of cardiovascular disease. To accomplish these goals, we will first provide some background about the relationship between chronic kidney disease and CVD. Next, we will discuss the value of estimating glomerular filtration rate (GFR) as a better measure of overall kidney function as opposed to ...
Source Cite
Published on Dec 1, 2018in American Journal of Kidney Diseases 6.65
Matthew R. Weir28
Estimated H-index: 28
(UMB: University of Maryland, Baltimore),
Jay I. Lakkis2
Estimated H-index: 2
(U.H.: University of Hawaii at Manoa)
+ 4 AuthorsElaine Ku10
Estimated H-index: 10
(UCSF: University of California, San Francisco)
Multiple clinical trials have demonstrated that renin-angiotensin system (RAS) blockade with either angiotensin-converting enzyme inhibitors or angiotensin receptor blockers effectively reduces chronic kidney disease (CKD) progression. However, most clinical trials excluded participants with advanced CKD (ie, estimated glomerular filtration rate [eGFR] 2 ). It is acknowledged that initiation of RAS blockade is often associated with an acute reduction in eGFR, which is thought to be functional, b...
2 Citations Source Cite
Published on Jul 1, 2018in Progress in Cardiovascular Diseases 6.16
Jay I. Lakkis2
Estimated H-index: 2
(U.H.: University of Hawaii at Manoa),
Mathew R. Weir1
Estimated H-index: 1
(UMB: University of Maryland, Baltimore)
Abstract Obesity is a systemic disease of the white adipose tissue, which has evolved into a global epidemic. It is associated with a plethora of adipocyte hormonal (adipokine) imbalances, dysregulation of the energy-balance system, imbalances in metabolic homeostasis, a pro-inflammatory state and multiple target organ damages. Clinically, the obesity phenotype is not homogenous and is more likely to represent a spectrum with varying degrees of metabolic un-health; metabolically-unhealthy obesit...
2 Citations Source Cite
Published on Feb 1, 2018in Current Cardiology Reports 2.40
Jay I. Lakkis2
Estimated H-index: 2
(U.H.: University of Hawaii at Manoa),
Matthew R. Weir28
Estimated H-index: 28
(UMB: University of Maryland, Baltimore)
Purpose of Review Hyperkalemia develops in a patient with systemic arterial hypertension (HTN) if one or more risk factors are present, namely chronic kidney disease (CKD) (especially severe stage 4-5 CKD), diabetes mellitus (DM), heart failure (HF), or pharmacological therapies that interfere with potassium homeostasis, mainly through renin-angiotensin-aldosterone inhibition (RAASi). Hyperkalemia is a considerable reason of morbidity (emergency department (ED) visits and hospitalizations) and p...
1 Citations Source Cite
1