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Afonso Caricati-Neto
Federal University of São Paulo
EndocrinologyChemistryVas deferensIschemiaMedicine
117Publications
14H-index
681Citations
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Publications 117
Newest
#1Francisco Sandro Menezes-Rodrigues (UNIFESP: Federal University of São Paulo)H-Index: 5
#2José Gustavo Padrão Tavares (UNIFESP: Federal University of São Paulo)H-Index: 3
Last. Afonso Caricati-Neto (UNIFESP: Federal University of São Paulo)H-Index: 14
view all 8 authors...
Abstract Most severe manifestations of COVID-19 cases, such as multiple organ failure and death, have been linked to coagulation dysfunction markers, such as platelet reduction and increases in prothrombin time, fibrin degradation products and, mainly, D-dimer [1]. A recent paper by Tang et al. [2] in this journal reported that heparin treatment reduced mortality of COVID-19 patients with elevated D-dimer; similar preliminary results have been reported elsewhere [3]. A mounting body of evidence ...
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#1Fulvio A. Scorza (UNIFESP: Federal University of São Paulo)H-Index: 32
#2Francisco Sandro Menezes-Rodrigues (UNIFESP: Federal University of São Paulo)H-Index: 5
Last. Afonso Caricati-Neto (UNIFESP: Federal University of São Paulo)H-Index: 14
view all 9 authors...
In 1817, the London surgeon and pharmacist James Parkinson published a 66-page-long booklet entitled “An Essay on the Shaking Palsy”, which contains the first detailed, clinical description of the shaking palsy, or “paralysis agitans”, which is currently known as Parkinson’s disease (PD) (). Two important facts James Parkinson probably did not consider at that time include the scientific progress of neuroscience over the past two centuries and the changes in the world’s population aging since th...
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#1Francisco Sandro Menezes-Rodrigues (UNIFESP: Federal University of São Paulo)H-Index: 5
#2José Gustavo Padrão Tavares (UNIFESP: Federal University of São Paulo)H-Index: 3
Last. Afonso Caricati-Neto (UNIFESP: Federal University of São Paulo)H-Index: 14
view all 10 authors...
Source
#1Afonso Caricati-Neto (UNIFESP: Federal University of São Paulo)H-Index: 14
#2Paolo Ruggero Errante (UNIFESP: Federal University of São Paulo)H-Index: 3
Last. Francisco Sandro Menezes-Rodrigues (UNIFESP: Federal University of São Paulo)H-Index: 5
view all 3 authors...
Ischemic heart diseases (IHD) are the leading cause of death worldwide. Although the principal form of treatment of IHD is myocardial reperfusion, the recovery of coronary blood flow after ischemia can cause severe and fatal cardiac dysfunctions, mainly due to the abrupt entry of oxygen and ionic deregulation in cardiac cells. The ability of these cells to protect themselves against injury including ischemia and reperfusion (I/R), has been termed “cardioprotection”. This protective response can ...
6 CitationsSource
#1Francisco Sandro Menezes-Rodrigues (UNIFESP: Federal University of São Paulo)H-Index: 5
#2Cristiane S Scorza (UNIFESP: Federal University of São Paulo)H-Index: 1
Last. Fulvio A. Scorza (UNIFESP: Federal University of São Paulo)H-Index: 32
view all 7 authors...
: Parkinson's disease (PD) is one of the most common age-related neurodegenerative disorders. Several studies over the last few years have shown that PD is accompanied by high rates of premature death compared with healthy controls. Death in PD patients is usually caused by determinant factors such as pneumonia, and cerebrovascular and cardiovascular diseases. During recent years it has emerged that dehydration may also contribute to mortality in PD. Interestingly, it has been documented that a ...
1 CitationsSource
#1Francisco Sandro Menezes-Rodrigues (UNIFESP: Federal University of São Paulo)H-Index: 5
#2Paolo Ruggero Errante (UNIFESP: Federal University of São Paulo)H-Index: 3
Last. Afonso Caricati-Neto (UNIFESP: Federal University of São Paulo)H-Index: 14
view all 9 authors...
PURPOSE: To evaluate the cardioprotective response of the pharmacological modulation of β-adrenergic receptors (β-AR) in animal model of cardiac ischemia and reperfusion (CIR), in spontaneously hypertensive (SHR) and normotensive (NWR) rats. METHODS: CIR was induced by the occlusion of left anterior descendent coronary artery (10 min) and reperfusion (75 min). The SHR was treated with β-AR antagonist atenolol (AT, 10 mg/kg, IV) 5 min before CIR, and NWR were treated with β-AR agonist isoproteren...
1 CitationsSource
#1Francisco Sandro Menezes-Rodrigues (UNIFESP: Federal University of São Paulo)H-Index: 5
#2Paolo Ruggero Errante (UNIFESP: Federal University of São Paulo)H-Index: 3
Last. Murched Omar Taha (UNIFESP: Federal University of São Paulo)H-Index: 13
view all 11 authors...
This work aimed to discuss the gains obtained by students of higher education in the understanding and assimilation of fundamental concepts in health care courses based on the use of the problem - based learning method (PBLM). A bibliographic survey was carried out in books obtained in the library of the Anhanguera University of Sao Paulo, theses, journals and scientific articles that were available in the scientific bases Scielo and Google Scholar, using as descriptor "method of learning based ...
Source
#1José Gustavo Padrão Tavares (UNIFESP: Federal University of São Paulo)H-Index: 3
#2Paolo Ruggero Errante (UNIFESP: Federal University of São Paulo)H-Index: 3
Last. Afonso Caricati-Neto (UNIFESP: Federal University of São Paulo)H-Index: 14
view all 8 authors...
PURPOSE: To investigate the cardioprotective effects of ischemic preconditioning (preIC) and postconditioning (postIC) in animal model of cardiac ischemia/reperfusion. METHODS: Adult rats were submitted to protocol of cardiac ischemia/reperfusion (I/R) and randomized into three experimental groups: cardiac I/R (n=33), preCI + cardiac I/R (n=7) and postCI + cardiac I/R (n=8). After this I/R protocol, the incidence of ventricular arrhythmia (VA), atrioventricular block (AVB) and lethality (LET) wa...
2 CitationsSource
#1Carlos Marcelo Gurjão de Godoy (UNIFESP: Federal University of São Paulo)H-Index: 3
#2Ênio R. Vasques (USP: University of São Paulo)H-Index: 4
Last. Ivarne L.S. Tersariol (UNIFESP: Federal University of São Paulo)H-Index: 27
view all 10 authors...
Background: Blockage of the Na+/Ca2+ exchanger (NCX) is used to determine the role of NCX in arrhythmogenesis. Trisulfated heparin disaccharide (TD) and Low Molecular Weight Heparins (LMWHs) can directly interact with the NCX and accelerate its activity. Objective: In this work, we investigated the antiarrhythmic effect of heparin oligosaccharides related to the NCX activity. Methods: The effects of heparin oligosaccharides were tested on the NCX current (patch clamping) and intracellular calciu...
3 CitationsSource
#1Francisco Sandro Menezes-Rodrigues (UNIFESP: Federal University of São Paulo)H-Index: 5
#2Paolo Ruggero Errante (UNIFESP: Federal University of São Paulo)H-Index: 3
Last. Afonso Caricati-Neto (UNIFESP: Federal University of São Paulo)H-Index: 14
view all 14 authors...
PURPOSE: To evaluate in vivo animal model of cardiac ischemia/reperfusion the cardioprotective activity of pancreatic lipase inhibitor of the orlistat. METHODS: Adult male Wistar rats were anesthetized, placed on mechanical ventilation and underwent surgery to induce cardiac I/R by obstructing left descending coronary artery followed by reperfusion to evaluation of ventricular arrhythmias (VA), atrioventricular block (AVB) and lethality (LET) with pancreatic lipase inhibitor orlistat (ORL). At t...
3 CitationsSource
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