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Mathew R. Weir
University of Maryland, Baltimore
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Published on Jul 1, 2018in Progress in Cardiovascular Diseases 6.75
Jay I. Lakkis2
Estimated H-index: 2
(U.H.: University of Hawaii at Manoa),
Mathew R. Weir1
Estimated H-index: 1
(UMB: University of Maryland, Baltimore)
Abstract Obesity is a systemic disease of the white adipose tissue, which has evolved into a global epidemic. It is associated with a plethora of adipocyte hormonal (adipokine) imbalances, dysregulation of the energy-balance system, imbalances in metabolic homeostasis, a pro-inflammatory state and multiple target organ damages. Clinically, the obesity phenotype is not homogenous and is more likely to represent a spectrum with varying degrees of metabolic un-health; metabolically-unhealthy obesit...
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