Anne Schöler
Humboldt University of Berlin
CancerPathologyDNA methylationAdenocarcinomaBiology
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Publications 3
#1Viktoria Ruf (LMU: Ludwig Maximilian University of Munich)H-Index: 3
#2Anne Schöler (DKFZ: German Cancer Research Center)H-Index: 2
Last. Ulrich Schüller (UHH: University of Hamburg)H-Index: 7
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#1Philipp Jurmeister (Charité)H-Index: 3
#2Anne Schöler (Humboldt University of Berlin)H-Index: 2
Last. David Capper (DKFZ: German Cancer Research Center)H-Index: 8
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Pulmonary enteric adenocarcinoma is a rare non-small cell lung cancer subtype. It is poorly characterized and cannot be distinguished from metastatic colorectal or upper gastrointestinal adenocarcinomas by means of routine pathological methods. As DNA methylation patterns are known to be highly tissue specific, we aimed to develop a methylation-based algorithm to differentiate these entities. To this end, genome-wide methylation profiles of 600 primary pulmonary, colorectal, and upper gastrointe...
3 CitationsSource
#1David CapperH-Index: 55
#2Damian Stichel (DKFZ: German Cancer Research Center)H-Index: 11
Last. Andreas von Deimling (DKFZ: German Cancer Research Center)H-Index: 83
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Recently, we described a machine learning approach for classification of central nervous system tumors based on the analysis of genome-wide DNA methylation patterns [6]. Here, we report on DNA methylation-based central nervous system (CNS) tumor diagnostics conducted in our institution between the years 2015 and 2018. In this period, more than 1000 tumors from the neurosurgical departments in Heidelberg and Mannheim and more than 1000 tumors referred from external institutions were subjected to ...
27 CitationsSource