Sean Wharton
University of Michigan
Publications 6
#1Sean Wharton (UM: University of Michigan)H-Index: 2
#2Christy Costanian (UM: University of Michigan)
Last.Rebecca A. G. Christensen (UPenn: University of Pennsylvania)H-Index: 1
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The prevalence of obesity has been increasing globally. Due to the negative health effects, obesity has been recognized as a major public health concern. Obesity is defined as a body mass index (BMI) of greater than or equal to 30 kg/m2. The location (i.e., abdominal) and type of excess weight contribute to ill-health; thus methods such as waist circumference and body fat measurements are used in the assessment of obesity. In relation to obesity and type 2 diabetes (T2D), genetics, physical acti...
#1Kathy Do (UM: University of Michigan)H-Index: 1
#2Ruth E. Brown (UM: University of Michigan)H-Index: 2
Last.Jennifer L. Kuk (UM: University of Michigan)H-Index: 6
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Previous literature suggests the beneficial effects of fitness on abdominal obesity may be attenuated in obesity and abolished in severe obesity. It is unclear whether the beneficial association between fitness and health is similarly present in those with mild and severe obesity. Patients from the Wharton Medical Clinic (n = 853) completed a clinical examination and maximal treadmill test. Patients were categorized into fit and unfit based on age- and sex-categories and body mass index (BMI) cl...
1 CitationsSource
#1Jash S. Parikh (UM: University of Michigan)
#2Arshdeep K. Randhawa (UM: University of Michigan)
Last.Jennifer L. Kuk (UM: University of Michigan)H-Index: 6
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Introduction. One in three US adults is living with obesity or hypertension, and more than 75% of hypertensive individuals are using antihypertensive medications. Therefore, it is important to examine blood pressure (BP) differences in populations that are using these medications with differing obesity status. Aim. We examined whether BP attained when using various antihypertensive medications varies amongst different body mass index (BMI) categories and whether antihypertensive medication use i...
1 CitationsSource
Current methods for the treatment of excess weight can involve healthy behavior changes, pharmacotherapy, and surgical interventions. Many individuals are able to lose some degree of weight through behavioral changes; however, they are often unable to maintain their weight loss long-term. This is in part due to physiological processes that cannot be addressed through behavioral changes alone. Bariatric surgery, which is the most successful treatment for excess weight to date, does result in phys...
5 CitationsSource
#1Rebecca H. Liu (York University)H-Index: 1
#2Sean Wharton (UM: University of Michigan)H-Index: 2
Last.Jennifer L. Kuk (York University)H-Index: 30
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Objective It is unclear whether all obese individuals should be prescribed weight loss (WL) treatment. The effect of a clinically significant WL of 5% on metabolic factors among metabolically normal and abnormal overweight and obese (MNO and MAO) individuals was examined. Design and Methods The sample included 392 overweight and obese adults from the Wharton Medical Clinic. MAO was defined as having one or more clinically relevant aberrations in glucose, triglycerides, blood pressure (BP), high-...
23 CitationsSource