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Heitor Albergoni Da Silveira
University of São Paulo
14Publications
Publications 28
Newest
Objective This study aims to investigate whether levels of multiples inflammatory mediators differed among patients with proliferative verrucous leukoplakia (PVL), oral leukoplakia (OL), oral squamous cell carcinoma (OSCC), and inflammatory fibrous hyperplasia (control group). Study Design The study includes frozen biopsy fragments of 12 PVL, 13 OL, 8 OSCC, and 7 control patients. A total of 26 mediators for the characterization of the Th1 / Th2 / Th9 / Th17 / Th22 / Treg cell subtypes and CD8+ ...
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Benign fibrous histiocytoma (BFH) is a benign mesenchymal neoplasm, composed of fibroblasts and histiocytes in variable proportions; it is uncommon to find BFH intraorally. To date, approximately 50 oral BFH cases have been reported; of them, 2 cases affected the palate. A 47-year-old female patient was referred for management of a slow-growing lesion in the soft palate region that appeared 1 year ago. The nodular lesion was asymptomatic, well delimited, firm, and covered by normal mucosa. Radio...
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Neurofibroma is a common cutaneous benign tumor of neural origin, and sporadic cases of fatty variants have been reported. A 56-year-old white woman was referred for evaluation of a nonulcerated submucosal nodule on the hard palate with 2 years of duration without symptoms. Her medical and family history was noncontributory. Intraoral examination revealed a nodular submucosal mass covered by normal-appearing mucosa measuring 2 cm in greatest dimension and resilient in consistency. Radiographic e...
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Objective Oropharyngeal squamous cell carcinomas (OPSCCs), especially those expressing human papilloma virus (HPV), are associated with a better prognosis than HPV-negative OPSCC and oral squamous cell carcinoma (OSCC). Among them, OPSCC often presents nonkeratinizing and hybrid than keratinizing histologic subtypes, as well as higher proliferation index. Thus, this study aims to analyze the relationship of epithelial-mesenchymal transition (EMT) and cell proliferation markers in OPSCC and OSCC....
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Epidermoid cysts (ECs) are rare and occur in the head and neck region with an incidence from 1.6% to 7%. In the oral cavity, EC represents less than 0.01% of all cysts. To date, approximately 80 EC cases have been reported. We report a case of a 26-year-old man who developed a large EC in the midline floor of the mouth, leading to speech and swallowing difficulties and causing swelling in the submental region. Ultrasonography and fine needle aspiration confirmed the cystic nature of the lesion. ...
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Pseudolymphoma (PL) is a benign reactive lymphoproliferative disease secondary to known or unknown stimuli mimicking a lymphomatous-appearing picture with potential misdiagnosis of overt lymphoma. A 64-year-old white man was referred for evaluation of ulceration on the left side of the buccal mucosa with 1 week of duration. The medical history revealed Alzheimer disease treated with donepezil and vildagliptin. Regional lymphadenopathy was absent and computerized tomography (CT) scans did not sho...
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Green pigmented teeth are considered an unusual condition that can affect primary and permanent teeth. The condition may affect patients with severe liver dysfunction associated with increased levels of bilirubin. A 21-month-old female patient was referred for evaluation of severe green discoloration of all her primary teeth. Her medical history revealed premature birth at 31 weeks of gestation in addition to an episode of early sepsis and neonatal jaundice. The girl developed necrotizing entero...
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Plasma cell cheilitis (PCC) is an unusual benign plasma cell proliferative disease of an unknown etiology that clinically presents as erythematous-violaceous plaques, ulcerations, or eruptions often affecting the lower lip. PCC is known to respond poorly to corticosteroid treatment. A 43-year-old male presented with multiple painful hemorrhagic crusts on the lower lip that had developed over 1 month. An incisional biopsy was performed and microscopy showed a bandlike inflammatory cell infiltrati...
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The peripheral ameloblastoma, desmoplastic histologic type, is a rare, benign tumor among the odontogenic tumors. Both the mandible and maxilla can be affected; it is characterized by slow growth, and usually is asymptomatic. A 58-year-old male patient was referred presenting with a painless nodule in the gingiva. Intraoral examination revealed an extraosseous submucosal nodule with 10 × 10 mm located at the mucus-gingival junction on the right side of the mandible. An excisional biopsy was perf...
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Proliferative verrucous leukoplakia (PVL) may be difficult to diagnose in early stages because of the lack of specific features. Our aim was to compare the clinicopathologic features and inflammatory intensity between PVL and oral leukoplakia (OL). Clinical data were retrospectively collected from archives. The intensity of inflammatory infiltrate, the inflammatory cell counting was compared between the groups with the diagnosis of PVL and oral leukoplakia (OL). The intensity of the inflammatory...
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