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Daniel Oliver
Nottingham Trent University
2Publications
1H-index
1Citations
Publications 2
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#1Daniel Oliver (NTU: Nottingham Trent University)H-Index: 1
#2Monika Michaelis (NTU: Nottingham Trent University)H-Index: 2
Last.Carole C. Perry (NTU: Nottingham Trent University)H-Index: 44
view all 5 authors...
Polypeptide based biosilica composites show promise as next generation multi-functional nano-platforms for diagnostics and bio-catalytic applications. Following the identification of a strong silica binder (LDHSLHS) by phage display, we conduct structural analysis of the polypeptide at the interface with amorphous silica nanoparticles in an aqueous environment. Our approach relies on modelling infrared and Raman spectral responses using predictions of molecular dynamics simulations and quantum s...
#1Anna Sola-Rabada (NTU: Nottingham Trent University)H-Index: 3
#2Monika Michaelis (NTU: Nottingham Trent University)H-Index: 2
Last.Carole C. Perry (NTU: Nottingham Trent University)H-Index: 44
view all 7 authors...
In this contribution, the effect of silica particle size (28 and 210 nm) and surface chemistry (i.e., hydroxyl, methyl, or amino groups) on peptide binding response is studied with a specific emphasis on the effect of the extent of functionalization on binding. Exhaustive characterization of the silica surfaces was crucial for knowledge of the chemistry and topography of the solid surface under study and, thus, to understand their impact on adsorption and the conformational ensemble of the pepti...
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