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Yang Cs
RadicalOxidative stressHydroxyl radicalMicrodialysisGlutathione
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The effect of acute thermal injury on subcutaneous oxidative stress, in anesthetized rats, was evaluated. A microdialysis probe was implanted in the subcutaneous tissue for continuous sampling of interstitial fluids, and the microdialysates were injected onto either an on-line or an off-line high performance liquid chromatography system. Hydroxyl radicals, glutathione, and ascorbic acid concentrations in the microdialysates were analyzed. Acute thermal injury was induced by skin contact of a hot...
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