Alison Offer
Clinical Trial Service Unit
12Publications
7H-index
444Citations
Publications 12
Newest
Published on Aug 1, 2015in European Heart Journal 23.43
S Parish54
Estimated H-index: 54
,
Alison Offer7
Estimated H-index: 7
+ 8 AuthorsRory Collins128
Estimated H-index: 128
Published on May 22, 2012in Circulation 18.88
S Parish54
Estimated H-index: 54
(Clinical Trial Service Unit),
Alison Offer7
Estimated H-index: 7
(Clinical Trial Service Unit)
+ 5 AuthorsRory Collins128
Estimated H-index: 128
(Clinical Trial Service Unit)
Background—Low-density lipoprotein (LDL) cholesterol and high-density lipoprotein (HDL) cholesterol are established risk factors for vascular disease, but lipoprotein particle concentrations may be stronger determinants of risk. Methods and Results—Associations between vascular events and baseline concentrations of cholesterol fractions, apolipoproteins B and A1, and lipoprotein particles assessed by nuclear magnetic resonance were considered in the Heart Protection Study randomized trial of sim...
130 Citations Source Cite
Published on Apr 1, 2012in International Journal of Epidemiology 8.36
Zhengming Chen43
Estimated H-index: 43
(Chinese Center for Disease Control and Prevention),
Gonghuan Yang7
Estimated H-index: 7
(Chinese Center for Disease Control and Prevention)
+ 6 AuthorsGary Whitlock26
Estimated H-index: 26
(Chinese Center for Disease Control and Prevention)
(HRs) and 95% confidence intervals (95% CIs) per 5 kg/m 2 calculated within either a lower (15 to <23.5 kg/m 2 ) or higher (23.5 to <35 kg/m 2 ) range. Results The association between BMI and all-cause mortality was U-shaped with the lowest mortality at � 22.5–25 kg/m 2 . In the lower range, 5 kg/m 2 higher BMI was associated with 14% lower mortality (HR 0.86, 95% CI 0.82–0.91); in the upper range, it was associated with 27% higher mortality (HR 1.27, 95% CI 1.15–1.40). The absolute excess morta...
70 Citations Source Cite
Published on Jan 1, 2012in European Heart Journal 23.43
Jemma C. Hopewell37
Estimated H-index: 37
,
Alison Offer7
Estimated H-index: 7
+ 7 AuthorsGrp H-Tc.1
Estimated H-index: 1
7 Citations
Published on Feb 1, 2011in Scopus
John F. Peden43
Estimated H-index: 43
,
Martin Farrall83
Estimated H-index: 83
+ 99 AuthorsJemma C. Hopewell37
Estimated H-index: 37
1 Citations Source Cite
Published on Sep 1, 2009in European Heart Journal 23.43
S Parish54
Estimated H-index: 54
(Clinical Trial Service Unit),
Richard Peto152
Estimated H-index: 152
(Clinical Trial Service Unit)
+ 8 AuthorsPeter Sleight87
Estimated H-index: 87
(Clinical Trial Service Unit)
Aims Plasma levels of apolipoprotein B (apoB), the main surface protein on LDL particles, and LDL-C, the amount of cholesterol in those particles, are closely correlated and, considered separately, are positive risk factors. Plasma levels of apolipoprotein A1, the main surface protein on HDL particles, and HDL-C, the amount of cholesterol in those particles, are also closely correlated with each other and, considered separately, are negative risk factors. The interdependence of these four risk f...
69 Citations Source Cite
Published on Mar 1, 2008in Stroke 6.24
Maigeng Zhou39
Estimated H-index: 39
(Clinical Trial Service Unit),
Alison Offer7
Estimated H-index: 7
(Clinical Trial Service Unit)
+ 7 AuthorsZhengming Chen43
Estimated H-index: 43
(Clinical Trial Service Unit)
Background and Purpose— Despite previous investigations, substantial uncertainty remains about the relation between body mass index (BMI) and stroke, especially in populations with a relatively low BMI but a high stroke rate. Methods— A nationally representative prospective study of mortality included 212 000 Chinese men 40 to 79 years old without known cardiovascular disease in 1990 to 1991 who were followed up for 10 years. Standardized hazard ratios were calculated for stroke mortality by bas...
48 Citations Source Cite
Published on Dec 4, 2007in International Journal of Cancer 7.36
Margaret Smith16
Estimated H-index: 16
(Clinical Trial Service Unit),
Maigeng Zhou39
Estimated H-index: 39
(Centers for Disease Control and Prevention)
+ 6 AuthorsZhengming Chen43
Estimated H-index: 43
(Clinical Trial Service Unit)
Several epidemiological studies have reported on the association between body mass index (BMI) and risk of esophageal cancer, but these were mostly in Western populations where many are overweight or obese. There is little direct evidence about the relationship in China where the mean BMI is relatively low and the disease rate is high. We examined the data from a populationbased prospective study of 220,000 Chinese men aged 40–79 without a previous history of cancer (mean BMI 21.7 kg/m 2 ), whic...
69 Citations Source Cite
Published on Feb 1, 2006in International Journal of Epidemiology 8.36
Zhengming Chen43
Estimated H-index: 43
,
Maigeng Zhou39
Estimated H-index: 39
+ 9 AuthorsRichard Peto152
Estimated H-index: 152
Conclusions Lower BMI is associated with lower IHD risk among people in the so-called normal range of BMI values (20–25 kg/m 2 ), but below that range the association may well
43 Citations Source Cite
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