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Valeriya Rakhmanova
Inha University
Mechanistic target of rapamycinDegranulationCell growthPI3K/AKT/mTOR pathwayBiology
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Abstract Mast cells express high-affinity IgE receptor (FceRI) on their surface, cross-linking of which leads to the immediate release of proinflammatory mediators such as histamine but also late-phase cytokine secretion, which are central to the pathogenesis of allergic diseases. Despite the growing evidences that mammalian target of rapamycin (mTOR) plays important roles in the immune system, it is still unclear how mTOR signaling regulates mast cell function. In this study, we investigated th...
1 CitationsSource
#1Valeriya Rakhmanova (IIT: Inha University)
#2Mirim Jin (Gachon University)H-Index: 15
Last. Jinwook Shin (IIT: Inha University)H-Index: 18
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