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Ankita Srivastava
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#1Kasi ManikandanH-Index: 2
#2Deepika Prasad (IISc: Indian Institute of Science)H-Index: 1
Last.Krishna M. SinhaH-Index: 18
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Cyclic di-GMP and cyclic di-AMP are second messengers produced by a wide variety of bacteria. They influence bacterial cell survival, biofilm formation, virulence and bacteria-host interactions. However, many of their cellular targets and biological effects are yet to be determined. A chemical proteomics approach revealed that Mycobacterium smegmatis RecA (MsRecA) possesses a high-affinity cyclic di-AMP binding activity. We further demonstrate that both cyclic di-AMP and cyclic di-GMP bind speci...
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