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Clara Nassrin Kriebel
Goethe University Frankfurt
2Publications
1H-index
5Citations
Publications 2
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#1Jagdeep Kaur (Goethe University Frankfurt)H-Index: 3
#2Clara Nassrin Kriebel (Goethe University Frankfurt)H-Index: 1
Last.Clemens Glaubitz (Goethe University Frankfurt)H-Index: 32
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Abstract Krokinobacter eikastus rhodopsin 2 (KR2) is a pentameric, light-driven ion pump, which selectively transports sodium or protons. The mechanism of ion selectivity and transfer is unknown. By using conventional as well as dynamic nuclear polarization (DNP)-enhanced solid-state NMR, we were able to analyse the retinal polyene chain between positions C10 and C15 as well as the Schiff base nitrogen in the KR2 resting state. In addition, 50% of the KR2 13C and 15N resonances could be assigned...
#1Marvin Asido (Goethe University Frankfurt)
#2Peter Eberhardt (Goethe University Frankfurt)H-Index: 2
Last.Josef Wachtveitl (Goethe University Frankfurt)H-Index: 37
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We report a comparative study on the structural dynamics of the light-driven sodium pump Krokinobacter eikastus rhodopsin 2 wild type under sodium and proton pumping conditions by means of time-resolved IR spectroscopy. The kinetics of KR2 under sodium pumping conditions exhibits a sequential character, whereas the kinetics of KR2 under proton pumping conditions involves several equilibrium states. The sodium translocation itself is characterized by major conformational changes of the protein ba...
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