Zhi-feng Zhong
Fujian Medical University
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Publications 3
#1Zhi-feng Zhong (Fujian Medical University)H-Index: 1
#2Jing HanH-Index: 3
Last. Li-Dian Chen (FJUTCM: Fujian University of Traditional Chinese Medicine)H-Index: 3
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Salidroside, a phenylpropanoid glycoside, is a main bioactive component of Rhodiola rosea L. Previous studies have indicated that salidroside has prominent anti-stroke effects in cerebral ischemia/reperfusion models. But the underline mechanisms involved are not well understood. This study was designed to illustrate the anti-stroke effects of salidroside on MCAO-induced models in rats and its potential mechanisms on dopaminergic system. We discovered that administration with salidroside increase...
: Recovery following stroke involves neurogenesis and axonal remodeling within the ischemic brain. Gualou Guizhi decoction (GLGZD) is a Chinese traditional medicine used for the treatment of post-stroke limb spasm. GLGZD has been reported to have neuroprotective effects in cerebral ischemic injury. However, the effects of GLGZD on neurogenesis and axonal remodeling following cerebral ischemia remain unknown. In this study, a rat model of focal cerebral ischemia/reperfusion was established by mid...
#1Zhi-feng ZhongH-Index: 1
#2Jing HanH-Index: 3
Last. Li-Dian ChenH-Index: 3
view all 6 authors...
: The primary objective of this review article was to summarize comprehensive information related to the neuropharmacological activity, mechanisms of action, toxicity, and safety of salidroside in medicine. A number of studies have revealed that salidroside exhibits neuroprotective activities, including anti-Alzheimer's disease, anti-Parkinson's disease, anti-Huntington's disease, anti-stroke, anti-depressive effects, and anti-traumatic brain injury; it is also useful for improving cognitive fun...
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