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Jun Xu
Peking University
6Publications
2H-index
16Citations
Publications 6
Newest
#1Yang SongH-Index: 2
#2Zhe WuH-Index: 2
Last.Yulan LiuH-Index: 6
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#1Zhe Wu (PKU: Peking University)H-Index: 2
#2Jun Xu (PKU: Peking University)H-Index: 2
Last.Yulan Liu (PKU: Peking University)H-Index: 6
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2 CitationsSource
#1Lin Su (PKU: Peking University)H-Index: 1
#2Zhe Wu (PKU: Peking University)H-Index: 2
Last.Yulan Liu (PKU: Peking University)H-Index: 6
view all 8 authors...
Abstract Non-alcoholic fatty liver disease (NAFLD) is characterized by altered intestinal microbiota and intestinal immune disorder. Here we investigated the role of mesenteric lymph node (MLN) CD4+ T lymphocytes in NAFLD. In high fat diet (HFD)-fed mice, the percentage ratios of Th1 to Th2 cells and Th17 to Treg cells were imbalanced in MLNs. Co-culture assays showed MLN CD4+ T lymphocytes from HFD-fed mice tended to migrate to the liver and promoted hepatic inflammation. Adoptive transfer of M...
1 CitationsSource
#1Zhe Wu (PKU: Peking University)H-Index: 2
#2Jiang Tan (PKU: Peking University)H-Index: 2
Last.Yulan Liu (PKU: Peking University)H-Index: 6
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The mesenteric adipose tissue (MAT) lies between the gut and liver and plays a critical role in hepatic metabolic diseases. In the present study, we found that the MAT was prone to inflammation in ...
2 CitationsSource
#1Jun Xu (PKU: Peking University)H-Index: 2
#2Ning Chen (PKU: Peking University)H-Index: 1
Last.Yulan Liu (PKU: Peking University)H-Index: 6
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Background The aim of this study was to clarify the effect of 5-aminosalicylic acid (5-ASA) treatment on gut bacterial microbiota in patients with ulcerative colitis (UC). Methods A total of 57 UC patients, including 20 untreated and 37 5-ASA-treated, were recruited into an exploration cohort. We endoscopically collected both noninflamed and inflamed mucosal samples from all patients, and compared the gut bacterial profiles using 16S rDNA sequencing. Ten untreated UC patients were then treated w...
11 CitationsSource
#1Zhe WuH-Index: 2
#2Yang SongH-Index: 2
Last.Yulan LiuH-Index: 6
view all 7 authors...
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