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Christina C.-W. Poon
Hong Kong Polytechnic University
Akt/PKB signaling pathwayGenisteinIcariinEstrogen receptorPI3K/AKT/mTOR pathway
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Publications 3
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#1Li-Ping Zhou (PolyU: Hong Kong Polytechnic University)H-Index: 4
#2Christina C.-W. Poon (PolyU: Hong Kong Polytechnic University)H-Index: 1
Last. Man-Sau Wong (PolyU: Hong Kong Polytechnic University)H-Index: 33
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#1Man-Sau Wong (PolyU: Hong Kong Polytechnic University)H-Index: 33
#2Christina C.-W. Poon (PolyU: Hong Kong Polytechnic University)H-Index: 1
Last. Hui-Hui Xiao (PolyU: Hong Kong Polytechnic University)H-Index: 7
view all 4 authors...
Demands for natural products, in the form of botanicals, dietary supplements, and herbal medicine, for management of chronic diseases are increasing globally. Natural products might be an alternative for the management of bone health to meet the demands of a growing aging population. Different types of natural products, including Chinese herbal medicine decoctions, herbs, and isolated phytochemicals, have been demonstrated to exert bone protective effects. The most common types of bone protectiv...
Source
#1Ming-Xian Ho (PolyU: Hong Kong Polytechnic University)H-Index: 3
#2Christina C.-W. Poon (PolyU: Hong Kong Polytechnic University)H-Index: 1
Last. Man-Sau Wong (PolyU: Hong Kong Polytechnic University)H-Index: 33
view all 5 authors...
Genistein and icariin are flavonoid compounds that exhibit estrogen-like properties in inducing bone formation and reducing bone loss associated with estrogen deficiency in both preclinical and clinical studies. However, the mechanisms that are involved in mediating their estrogenic actions in bone cells are far from clear. The present study aimed to study the signaling pathways that mediate the estrogenic actions of genistein and icariin in osteoblastic cells. The effects of genistein and icari...
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