Einat Cinnamon
Francis Crick Institute
Publications 3
#1Einat Cinnamon (Francis Crick Institute)H-Index: 2
#2Rami Makki (Francis Crick Institute)H-Index: 2
Last.Alex P. Gould (Francis Crick Institute)H-Index: 5
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Cell growth and proliferation depend upon many different aspects of lipid metabolism. One key signaling pathway that is utilized in many different anabolic contexts involves Phosphatidylinositide 3-kinase (PI3K) and its membrane lipid products, the Phosphatidylinositol (3,4,5)-trisphosphates. It remains unclear, however, which other branches of lipid metabolism interact with the PI3K signaling pathway. Here, we focus on specialized fat metabolizing cells in Drosophila called larval oenocytes. In...
#1Rami MakkiH-Index: 2
#2Einat CinnamonH-Index: 2
Last.Alex P. Gould (Medical Research Council)H-Index: 1
view all 3 authors...
Oenocytes have intrigued insect physiologists since the nineteenth century. Many years of careful but mostly descriptive research on these cells highlights their diverse sizes, numbers, and anatomical distributions across Insecta. Contemporary molecular genetic studies in Drosophila melanogaster and Tribolium castaneum support the hypothesis that oenocytes are of ectodermal origin. They also suggest that, in both short and long germ-band species, oenocytes are induced from a Spalt major/Engraile...