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Annika Braun
Heidelberg University
Proinflammatory cytokineTumor necrosis factor alphaPhosphatidylcholineMucusInterleukin 8
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#1Irina Treede (Heidelberg University)H-Index: 1
#2Annika Braun (Heidelberg University)H-Index: 1
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Background Phosphatidylcholine (PC) is a major lipid of the gastrointestinal mucus layer. We recently showed that mucus from patients suffering from ulcerative colitis has low levels of PC. Clinical studies reveal that the therapeutic addition of PC to the colonic mucus using slow release preparations is beneficial. The positive role of PC in this disease is still unclear; however, we have recently shown that PC has an intrinsic anti-inflammatory property. It could be demonstrated that the exoge...
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