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Scott J. Weissman
Seattle Children's Research Institute
11Publications
5H-index
115Citations
Publications 11
Newest
Published on Mar 30, 2017in bioRxiv
Arianna Miles-Jay3
Estimated H-index: 3
(UW: University of Washington),
Scott J. Weissman5
Estimated H-index: 5
(Seattle Children's Research Institute)
+ 4 AuthorsDanielle M. Zerr10
Estimated H-index: 10
(Seattle Children's Research Institute)
Background: E. coli ST131-H30 is a globally important pathogen implicated in rising rates of multidrug resistance, especially fluoroquinolone resistance and extended-spectrum beta-lactamase (ESBL) production, among E. coli causing extraintestinal infections. Previous studies have focused on adults, especially the elderly, leaving the epidemiology of H30 among children undefined. Methods: We used clinical data and extraintestinal E. coli isolates from a case-control study conducted at four US fre...
Published on Jan 1, 2017in IDCases
Genevieve L. Buser7
Estimated H-index: 7
(Oregon Health Authority),
P. Maureen Cassidy5
Estimated H-index: 5
(Oregon Health Authority)
+ 10 AuthorsMansour Samadpour29
Estimated H-index: 29
(Forest Park)
Abstract The first Oregon case of New Delhi metallo-β-lactamase-1 (NDM-1)-producing Escherichia coli was reported during November 2013. Epidemiologic investigation revealed only local outpatient medical care and no travel outside Oregon for both the patient and his household contact. Environmental sampling discovered a matching isolate from the patient’s household vacuum cleaner, suggesting environmental persistence.
Published on Dec 1, 2016in Journal of global antimicrobial resistance 2.47
Joel E. Mortensen21
Estimated H-index: 21
(Cincinnati Children's Hospital Medical Center),
Barbara DeBurger2
Estimated H-index: 2
(Cincinnati Children's Hospital Medical Center)
+ 3 AuthorsScott J. Weissman5
Estimated H-index: 5
(Seattle Children's Research Institute)
Although carbapenem-resistant Enterobacteriaceae (CRE) have been recognised worldwide, there are important gaps in regional prevalence data. This study sought to determine the occurrence and type of CRE in the Cincinnati tri-state region. Clinical microbiology laboratories in the region screened patient stool and rectal swab samples using chromogenic screening agar. Isolates of Enterobacteriaceae resistant to carbapenems were characterised using molecular methods. Area institutions screened 1939...
Published on Sep 1, 2016
Scott J. Weissman5
Estimated H-index: 5
(Seattle Children's Research Institute),
Nellie I. Hansen29
Estimated H-index: 29
(RTP: Research Triangle Park)
+ 2 AuthorsBarbara J. Stoll85
Estimated H-index: 85
(Emory University)
Escherichia coli associated with early-onset sepsis (EOS) have historically been antibiotic-susceptible and K1-encapsulated. In the era of emerging antibiotic resistance, however, the clonal makeup of E coli associated with EOS has not been well characterized.Escherichia coli isolates were collected from 28 cases of EOS and early-onset meningitis (EOM) from April 2008 through December 2009, during a parent study conducted at National Institute of Child Health and Human Development Neonatal Resea...
Published on May 1, 2016in Journal of Microbiological Methods 1.80
Sara Ahmed1
Estimated H-index: 1
,
Thomas E. Besser48
Estimated H-index: 48
+ 3 AuthorsMargaret A. Davis24
Estimated H-index: 24
Abstract Multi-locus sequence typing (MLST) is a useful system for phylogenetic and epidemiological studies of multidrug-resistant E scherichia coli . Most studies utilize a seven-locus MLST, but an alternate two-locus typing method ( fumC and fimH ; CH typing) has been proposed that may offer a similar degree of discrimination at lower cost. Herein, we compare CH typing to the standard seven-locus method for typing commensal E. coli isolates from dairy cattle. In addition, we evaluated alternat...
Published on Jun 1, 2015in Infection Control and Hospital Epidemiology 2.86
Kristen A. Wendorf2
Estimated H-index: 2
(CDC: Centers for Disease Control and Prevention),
Meagan Kay6
Estimated H-index: 6
(Public Health – Seattle & King County)
+ 9 AuthorsKaye Eckmann2
Estimated H-index: 2
(Washington State Department of Health)
Published on May 29, 2014in Genome Announcements
Kirthi K. Kutumbaka3
Estimated H-index: 3
(Forest Park),
Sukkyun Han2
Estimated H-index: 2
(Forest Park)
+ 8 AuthorsRobert Vega3
Estimated H-index: 3
ABSTRACT A multidrug-resistant NDM-1 carbapenamase-producing Escherichia coli sequence type 131 (ST131) organism was obtained from vacuum cleaner dust collected from the home of a case patient. Here, we report the assembly and annotation of its genome.
Published on Apr 1, 2014in Journal of Medical Microbiology 1.93
Malaika L. Little1
Estimated H-index: 1
(Seattle Children's Research Institute),
Xuan Qin1
Estimated H-index: 1
(Seattle Children's Research Institute)
+ 1 AuthorsScott J. Weissman5
Estimated H-index: 5
(Seattle Children's Research Institute)
Klebsiella pneumoniae causes a range of clinical disease in paediatric patients and is of increasing concern due to growing antibiotic resistance, yet little is known about the relative distribution of commensal and pathogens throughout the population structure of K. pneumoniae. We conducted a prospective, observational study of 92 isolates from Seattle Children’s Hospital, including 49 disease isolates from blood and urine (13 and 36 isolates, respectively) and 43 colonization isolates from sto...
Published on Jun 1, 2013in Molecular Biology and Evolution 14.80
Sujay Chattopadhyay6
Estimated H-index: 6
(UW: University of Washington),
Fred Taub6
Estimated H-index: 6
(UW: University of Washington)
+ 2 AuthorsEvgeni V. Sokurenko35
Estimated H-index: 35
(UW: University of Washington)
Analysis of genetic differences (gene presence/absence and nucleotide polymorphisms) among strains of a bacterial species is crucial to understanding molecular mechanisms of bacterial pathogenesis and selecting targets for novel antibacterial therapeutics. However, lack of genome-wide association studies on large and epidemiologically well-defined strain collections from the same species makes it difficult to identify the genes under positive selection and define adaptive polymorphisms in those ...
Published on Mar 5, 2013in Mbio 6.75
Dagmara I. Kisiela11
Estimated H-index: 11
(UW: University of Washington),
Sujay Chattopadhyay19
Estimated H-index: 19
(UW: University of Washington)
+ 5 AuthorsEvgeni V. Sokurenko35
Estimated H-index: 35
(UW: University of Washington)
ABSTRACT Salmonella and Escherichia coli mannose-binding type 1 fimbriae exhibit highly similar receptor specificities, morphologies, and mechanisms of assembly but are nonorthologous in nature, i.e., not closely related evolutionarily. Their operons differ in chromosomal location, gene arrangement, and regulatory components. In the current study, we performed a comparative genetic and structural analysis of the major structural subunit, FimA, from Salmonella and E. coli and found that FimA pili...
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