Match!
Nguyen Phuong Thao
Vietnam Academy of Science and Technology
Organic chemistryChemistryBiochemistryStereochemistryBiology
138Publications
17H-index
1,379Citations
What is this?
Publications 129
Newest
#1Sang-Bin Lee (SKKU: Sungkyunkwan University)H-Index: 2
#2Seo Young Yang (CNU: Chungnam National University)H-Index: 12
Last. Hyun Ok Yang (KIST: Korea Institute of Science and Technology)H-Index: 19
view all 9 authors...
Cimicifuga dahurica has traditionally been used as an antipyretic, analgesic, and anti-inflammatory agent and as a treatment for uterine and anal prolapse. This study has investigated the potential beneficial effects of this medicinal plant and its components on Alzheimer’s disease (AD) with a focus on amyloid beta (Aβ) production and scopolamine-induced memory impairment in mice. An ethanol extract from C. dahurica roots decreased Aβ production in APP-CHO cells [Chinese hamster ovarian (CHO) ce...
Source
#1Pham Thi Mai Huong (VAST: Vietnam Academy of Science and Technology)H-Index: 3
#2Nguyen Viet Phong (VAST: Vietnam Academy of Science and Technology)H-Index: 1
Last. Chau Van Minh (VAST: Vietnam Academy of Science and Technology)H-Index: 23
view all 10 authors...
Using various chromatographic separations, four steroids including one new C20 steroid namely dendrodoristerol (1), were isolated from the Vietnamese nudibranch mollusk Dendrodoris fumata. The structure elucidation was confirmed by combination of spectroscopic experiments including 1D and 2D NMR, HR QTOF MS, and CD. Compound 1 was found to exhibit significant in vitro cytotoxic activity against six human cancer cell lines as HL-60, KB, LU-1, MCF-7, LNCaP, and HepG2. In addition, 1 induced HL-60 ...
Source
#1Nguyen Van Thanh (VAST: Vietnam Academy of Science and Technology)H-Index: 8
#2Nguyen Phuong Thao (VAST: Vietnam Academy of Science and Technology)H-Index: 17
Last. Chau Van Minh (VAST: Vietnam Academy of Science and Technology)H-Index: 23
view all 6 authors...
A new [7.7]paracyclophane (1), together with eight known compounds (2-9), were isolated from a MeOH extract of the sea snail Planaxis sulcatus (Born, 1780). Their structures were elucidated by HR-ESI-MS and NMR techniques as well as comparison with those reported in literatures. The absolute configuration of metabolite 1 was determined using ECD spectroscopy. Among nine compounds, 1 exhibited significant cytotoxicity toward all eight cancer cells tested with IC50 values between 1.81 and 3.80 µg/...
Source
#1Quang OngH-Index: 1
Last. Lam-Son Phan TranH-Index: 51
view all 4 authors...
Source
Being master regulators of gene expression, transcription factors (TFs) play important roles in determining plant growth, development and reproduction. To date, many TFs have been shown to positively mediate plant responses to environmental stresses. In the current study, the biological functions of a stress-responsive NAC [NAM (No Apical Meristem), ATAF1/2 (Arabidopsis Transcription Activation Factor1/2), CUC2 (Cup-shaped Cotyledon2)]-TF encoding gene isolated from soybean (GmNAC019) in relatio...
Source
#1Nguyen Cao NguyenH-Index: 1
#2Xuan Lan Thi HoangH-Index: 5
Last. Lam-Son Phan TranH-Index: 51
view all 7 authors...
The NAC (NAM, ATAF1/2, CUC2) transcription factors are widely known for their various functions in plant development and stress tolerance. Previous studies have demonstrated that genetic engineering can be applied to enhance drought tolerance via overexpression/ectopic expression of NAC genes. In the present study, the dehydration- and drought-inducible GmNAC109 from Glycine max was ectopically expressed in Arabidopsis (GmNAC109-EX) plants to study its biological functions in mediating plant ada...
1 CitationsSource
#1Le Duc Dat (Ton Duc Thang University)H-Index: 3
#2Ngo Viet Duc (Ton Duc Thang University)
Last. Nguyen Phuong Thao (VAST: Vietnam Academy of Science and Technology)H-Index: 17
view all 8 authors...
Abstract Two new megastigmane glycosides, laurusides E-F ( 1 and 3 ) and three known ones ( 2 , 5 , and 7 ), together with a new abscisic acid glycoside, lauruside G ( 4 ) and a known one ( 6 ), were isolated from a methanolic extract of Laurus nobilis L. leaves using various chromatographic techniques. The structures of these compounds were fully characterized using a combination of spectroscopic techniques including multinuclear and multidimensional NMR and mass spectrometry. All of the isolat...
Source
#1Le Ba Vinh (VAST: Vietnam Academy of Science and Technology)H-Index: 2
#2Nguyen Thi Minh Nguyet (CNU: Chungnam National University)H-Index: 2
Last. Young Ho Kim (CNU: Chungnam National University)H-Index: 61
view all 11 authors...
AbstractUsing various chromatographic techniques, a total of 15 compounds, including one novel megastigmane named tiliaceic acid A (1) and 14 known compounds, were isolated from the traditional med...
Source
#1Lai Hop Hieu (VAST: Vietnam Academy of Science and Technology)H-Index: 1
#2Nguyen Phuong Thao (VAST: Vietnam Academy of Science and Technology)H-Index: 17
Last. Chau Van Minh (VAST: Vietnam Academy of Science and Technology)H-Index: 23
view all 10 authors...
Abstract A new rhamnofolane-type diterpenoid (1) and a new phenolic derivative (2), together with eleven known compounds, were isolated from the leaves of E. cochinchinensis Lour. The chemical structures of these compounds were elucidated based on extensive spectroscopic analysis, including HR-QTOF-MS and NMR, and comparison with reported data. The inhibitory effects of compounds 1–13 on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cells were evaluated. As the obtain...
Source
#1Le Duc Dat (Ton Duc Thang University)H-Index: 3
#2Nguyen Thi Minh Tu (HUST: Hanoi University of Science and Technology)H-Index: 1
Last. Nguyen Phuong Thao (VAST: Vietnam Academy of Science and Technology)H-Index: 17
view all 13 authors...
Abstract A phytochemical investigation for the constituents of the stems of Millettia dielsiana Harms ex Diels resulted in the isolation of a new isoflavone glycoside, mildiside A (1), and 14 known compounds (2–15). Their chemical structures were determined using a combination of IR, NMR, MS, and optical rotation analysis, as well as comparison with the literature data. The ethanolic (EtOH) extract and several isolated compounds exert the inflammatory effect of nitric oxide (NO) production in li...
Source
12345678910