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Sushila Pachwania
Guru Jambheshwar University of Science and Technology
RepressorGene Expression ProcessDNADrug actionActivator (genetics)
1Publications
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7Citations
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#1Jai Devi (Guru Jambheshwar University of Science and Technology)H-Index: 6
#2Sushila Pachwania (Guru Jambheshwar University of Science and Technology)H-Index: 1
Abstract DNA interaction studies of organotin(IV) complexes have got tremendous attention during the recent years due to their anticancer and antitumor properties. Most of the chemotherapeutic organotins are DNA-targeted as they recognize specific DNA sequences, alter the local DNA structure, inhibit access to the activator or repressor protein and ultimately affect the gene expression process. The binding ability of organotin(IV) compounds with DNA depends on the coordination number and the nat...
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