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Francesca Cioppi
University of Florence
4Publications
1H-index
10Citations
Publications 4
Newest
#1Daniel Moreno-Mendoza (Autonomous University of Barcelona)H-Index: 2
#2Elena Casamonti (UniFI: University of Florence)H-Index: 2
Last.Csilla Krausz (UniFI: University of Florence)H-Index: 52
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The association between impaired spermatogenesis and TGCT has stimulated research on shared genetic factors. Y chromosome-linked partial AZFc deletions predispose to oligozoospermia and were also studied in TGCT patients with controversial results. In the largest study reporting the association between gr/gr deletion and TGCT, sperm parameters were unknown. Hence, it remains to be established whether this genetic defect truly represents a common genetic link between TGCT and impaired sperm produ...
1 CitationsSource
#1Francesca Cioppi (UniFI: University of Florence)H-Index: 1
#2Antoni Riera-Escamilla (Autonomous University of Barcelona)H-Index: 3
Last.Csilla Krausz (UniFI: University of Florence)H-Index: 52
view all 10 authors...
1 CitationsSource
#1Francesca Cioppi (UniFI: University of Florence)H-Index: 1
#2Elena Casamonti (UniFI: University of Florence)H-Index: 2
Last.Csilla Krausz (UniFI: University of Florence)H-Index: 52
view all 3 authors...
Spermatogenesis is a highly complex biological process during which germ cells undergo recurrent rounds of DNA replication and cell division that may predispose to random mutational events. Hence, germ cells are vulnerable to the introduction of a range of de novo mutations, in particular chromosomal aberrations, point mutations and small indels. The main mechanisms through which mutations may occur during spermatogenesis are (i) errors in DNA replication, (ii) inefficient repair of non-replicat...
Source
#1Csilla Krausz (UniFI: University of Florence)H-Index: 52
#2Francesca Cioppi (UniFI: University of Florence)H-Index: 1
Last.Antoni Riera-Escamilla (Autonomous University of Barcelona)H-Index: 3
view all 3 authors...
ABSTRACTIntroduction: Male infertility affects about 7% of the general male population, and it is a multifactorial, polygenic pathological condition. Known genetic factors, accounting for about 20–25% of male factor infertility, are present in each etiological category: i) hypothalamic-pituitary axis dysfunction; ii) quantitative and qualitative alterations of spermatogenesis; iii) ductal obstruction/dysfunction.Areas covered: All routinely available genetic tests are described. Indication for t...
8 CitationsSource
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