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Simone Sander
Heidelberg University
1Publications
1H-index
3Citations
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Published on Jun 1, 2018in Biochimica et Biophysica Acta3.79
Margarete Poppelreuther5
Estimated H-index: 5
(Heidelberg University),
Simone Sander1
Estimated H-index: 1
(Heidelberg University)
+ 14 AuthorsSusanne Domschke1
Estimated H-index: 1
(Heidelberg University)
Abstract ACSL3 is the only long chain fatty acyl-CoA synthetase consistently found on growing and mature lipid droplets (LDs), suggesting that this specific localization has biological relevance. Current models for LD growth propose that triglycerides are synthesized by enzymes at the LD surface, with activated fatty acids provided by LD localized ACSL3, thus allowing growth independent of the ER. Here, we tested this hypothesis by quantifying ACSL3 on LDs from human A431 cells. RNAi of ACSL3 re...
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