Miriam Sjåstad Langseth
University of Oslo
Neutrophil extracellular trapsUnstable anginaCoronary artery diseaseExtracellular TrapsMyocardial infarction
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Publications 4
#1Karsten E. Kluge (University of Oslo)
#2Miriam Sjåstad Langseth (University of Oslo)H-Index: 1
Last. Ragnhild Helseth (Oslo University Hospital)H-Index: 3
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#1Miriam Sjåstad Langseth (University of Oslo)H-Index: 1
#2Ragnhild Helseth (Oslo University Hospital)H-Index: 3
Last. Harald Arnesen (University of Oslo)H-Index: 48
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Neutrophil extracellular traps (NETs) have been implicated in atherothrombosis; however, their potential role as markers of risk is unclear. We investigated whether circulating NETs-related components associated with clinical outcome and hypercoagulability in ST-elevation myocardial infarction (STEMI). In this observational cohort study, STEMI patients admitted for PCI (n = 956) were followed for median 4.6 years, recording 190 events (reinfarction, unscheduled revascularization, stroke, heart f...
#1Ragnhild Helseth (Oslo University Hospital)H-Index: 3
#1R Helseth (Oslo University Hospital)H-Index: 1
Last. Ingebjørg Seljeflot (University of Oslo)H-Index: 44
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Background. The relevance of neutrophil extracellular traps (NETs) in acute ST-elevation myocardial infarction (STEMI) is unclear. We explored the temporal profile of circulating NET markers and their associations to myocardial injury and function and to adverse clinical events in STEMI patients. Methods and Results. In 259 patients, blood samples were drawn before and after PCI, on day 1, and after 4 months. Double-stranded deoxyribonucleic acid (dsDNA) and myeloperoxidase-DNA (MPO-DNA) were me...
1 CitationsSource
#1Miriam Sjåstad Langseth (University of Oslo)H-Index: 1
#2Trine B. Opstad (University of Oslo)H-Index: 10
Last. Ragnhild Helseth (University of Oslo)H-Index: 3
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BackgroundNeutrophil extracellular traps, comprising chromatin and granule proteins, have been implicated in atherothrombosis.Design and methodsWe investigated whether the circulating neutrophil extracellular traps markers, double-stranded DNA and myeloperoxidase-DNA were associated with clinical outcome and hypercoagulability in patients with stable coronary artery disease. Patients with angiographically verified stable coronary artery disease (n = 1001) were included. Follow-up was 2 years, re...
6 CitationsSource