Match!
Jiarui Wang
Stanford University
11Publications
4H-index
99Citations
Publications 11
Newest
#1Xiaofeng Zhou (Stanford University)H-Index: 1
#2Jiarui Wang (Stanford University)H-Index: 4
Last.Lucy Shapiro (Stanford University)H-Index: 75
view all 5 authors...
The cell cycle-regulated methylation state of Caulobacter DNA mediates the temporal control of transcriptional activation of several key regulatory proteins. Temporally controlled synthesis of the CcrM DNA methyltransferase and Lon-mediated proteolysis restrict CcrM to a specific time in the cell cycle, thereby allowing the maintenance of the hemimethylated state of the chromosome during the progression of DNA replication. We determined that a chromosomal DNA-based platform stimulates CcrM degra...
Source
#1Peter D. Dahlberg (Stanford University)H-Index: 13
#2Annina M. Sartor (Stanford University)H-Index: 1
Last.W. E. Moerner (Stanford University)H-Index: 74
view all 6 authors...
Single-molecule super-resolution fluorescence microscopy conducted in vitrified samples at cryogenic temperatures offers enhanced localization precision due to reduced photobleaching rates, a chemical-free and rapid fixation method, and the potential of correlation with cryogenic electron microscopy. Achieving cryogenic super-resolution microscopy requires the ability to control the sparsity of emissive labels at cryogenic temperatures. Obtaining this control presents a key challenge for the dev...
4 CitationsSource
#1Camille A. Bayas (Stanford University)H-Index: 1
#2Jiarui Wang (Stanford University)H-Index: 4
Last.W. E. Moerner (Stanford University)H-Index: 74
view all 6 authors...
We report the dynamic spatial organization of Caulobacter crescentus RNase E (RNA degradosome) and ribosomal protein L1 (ribosome) using 3D single-particle tracking and superresolution microscopy. RNase E formed clusters along the central axis of the cell, while weak clusters of ribosomal protein L1 were deployed throughout the cytoplasm. These results contrast with RNase E and ribosome distribution in Escherichia coli, where RNase E colocalizes with the cytoplasmic membrane and ribosomes accumu...
21 CitationsSource
#1Camille A. BayasH-Index: 1
#2Jiarui WangH-Index: 4
Last.W. E. MoernerH-Index: 74
view all 6 authors...
Source
#1Jiarui WangH-Index: 4
#2Lucy ShapiroH-Index: 75
Last.W. E. MoernerH-Index: 74
view all 3 authors...
Source
#1Annina M. SartorH-Index: 1
#2Peter D. DahlbergH-Index: 13
Last.W. E. MoernerH-Index: 74
view all 5 authors...
Source
#1Krishna C. Suddala (UM: University of Michigan)H-Index: 8
#2Jiarui Wang (UM: University of Michigan)H-Index: 4
Last.Nils G. WalterH-Index: 46
view all 4 authors...
Bacterial riboswitches couple small-molecule ligand binding to RNA conformational changes that widely regulate gene expression, rendering them potential targets for antibiotic intervention. Despite structural insights, the ligand-mediated folding mechanisms of riboswitches are still poorly understood. Using single-molecule fluorescence resonance energy transfer (smFRET), we have investigated the folding mechanism of an H-type pseudoknotted preQ1 riboswitch in dependence of Mg2+ and three ligands...
34 CitationsSource
Four days after the announcement of the 2014 Nobel Prize in Chemistry for “the development of super-resolved fluorescence microscopy” based on single molecule detection, the Single Molecule Analysis in Real-Time (SMART) Center at the University of Michigan hosted a “Principles of Single Molecule Techniques 2014” course. Through a combination of plenary lectures and an Open House at the SMART Center, the course took a snapshot of a technology with an especially broad and rapidly expanding range o...
Source
#1Rebecca M. Bartke (UM: University of Michigan)
#2Elizabeth L. Cameron (UM: University of Michigan)H-Index: 2
Last.Nils G. Walter (UM: University of Michigan)H-Index: 46
view all 26 authors...
Four days after the announcement of the 2014 Nobel Prize in Chemistry for “the development of super-resolved fluorescence microscopy” based on single molecule detection, the Single Molecule Analysis in Real-Time (SMART) Center at the University of Michigan hosted a “Principles of Single Molecule Techniques 2014” course. Through a combination of plenary lectures and an Open House at the SMART Center, the course took a snapshot of a technology with an especially broad and rapidly expanding range o...
Source
Source
12