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Priyanka S. Deshpande
Stanford University
AntigenAntibodyAcquired immune systemPopulationImmune system
2Publications
2H-index
190Citations
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Publications 2
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#1Carsten T. Charlesworth (Stanford University)H-Index: 3
#2Priyanka S. Deshpande (Stanford University)H-Index: 2
Last. Matthew H. Porteus (Stanford University)H-Index: 49
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The CRISPR–Cas9 system is a powerful tool for genome editing, which allows the precise modification of specific DNA sequences. Many efforts are underway to use the CRISPR–Cas9 system to therapeutically correct human genetic diseases1–6. The most widely used orthologs of Cas9 are derived from Staphylococcus aureus and Streptococcus pyogenes5,7. Given that these two bacterial species infect the human population at high frequencies8,9, we hypothesized that humans may harbor preexisting adaptive imm...
63 CitationsSource
#1Carsten T. Charlesworth (Stanford University)H-Index: 3
#2Priyanka S. Deshpande (Stanford University)H-Index: 2
Last. Matthew H. Porteus (Stanford University)H-Index: 49
view all 10 authors...
The CRISPR-Cas9 system has proven to be a powerful tool for genome editing allowing for the precise modification of specific DNA sequences within a cell. Many efforts are currently underway to use the CRISPR-Cas9 system for the therapeutic correction of human genetic diseases. The most widely used homologs of the Cas9 protein are derived from the bacteria Staphylococcus aureus (S. aureus) and Streptococcus pyogenes (S. pyogenes). Based on the fact that these two bacterial species cause infection...
74 CitationsSource
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