Wenjing Sun
Kunming Medical University
Caspase 1PyroptosisAMPKGastrodinBiology
What is this?
Publications 2
#1Wenjing Sun (Kunming Medical University)H-Index: 2
#2Hongquan Lu (Kunming Medical University)H-Index: 2
Last. Di Lu (Kunming Medical University)H-Index: 6
view all 8 authors...
Inflammation is a pivotal feature of myocardial reperfusion–induced microvascular injury and dysfunction. However, the molecular mechanisms by which myocardial reperfusion triggered inflammation remain incurable. The NLRP3 inflammasome is a key intracellular sensor that detection of cellular stress to activation of caspase-1, and consequent IL-1β maturation and pyroptotic cell death. Here, we showed that NLRP3 inflammasome played a key role in myocardial reperfusion–induced microvascular injury....
3 CitationsSource
#1Ping Yang (Kunming Medical University)H-Index: 3
#2Lu Ling (Kunming Medical University)H-Index: 1
Last. Di Lu (Kunming Medical University)H-Index: 6
view all 10 authors...
: Ginsenoside Rg1 (Rg1) has been widely used in a broad range of cardiovascular and cerebral-vascular diseases because of its unique therapeutic properties. However, the underlying mechanisms of Rg1 in the treatment of atherosclerosis have not been fully explored. This study sought to determine the precise molecular mechanisms on how Rg1 might be involved in regulating apoptosis in serum deprivation-induced Raw264.7 macrophages and primary bone marrow-derived macrophages. Results demonstrated th...
10 CitationsSource