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Shubha Ghosh Dastidar
University of Louisville
7Publications
2H-index
19Citations
Publications 7
Newest
#1Shubha Ghosh Dastidar (University of Louisville)H-Index: 2
#2Ganapathy Jagatheesan (University of Louisville)H-Index: 5
Last.Daniel J. Conklin (University of Louisville)H-Index: 28
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Hepatic glutathione S-transferases (GSTs) are dysregulated in human obesity, nonalcoholic fatty liver disease, and diabetes. The multifunctional GST pi-isoform (GSTP) catalyzes the conjugation of g...
#1Dennis R. Warner (University of Louisville)H-Index: 14
#2Huilin Liu (University of Louisville)H-Index: 3
Last.Irina A. KirpichH-Index: 17
view all 12 authors...
Alcoholic liver disease (ALD), a significant health problem, progresses through the course of several pathologies including steatosis, steatohepatitis, fibrosis, and cirrhosis. There are no effective FDA-approved medications to prevent or treat any stages of ALD, and the mechanisms involved in ALD pathogenesis are not well understood. Bioactive lipid metabolites play a crucial role in numerous pathological conditions, as well as in the induction and resolution of inflammation. Herein, a hepatic ...
#2Jeffrey B. WarnerH-Index: 2
Last.Irina A. KirpichH-Index: 17
view all 5 authors...
Both chronic and acute (binge) alcohol drinking are important health and economic concerns worldwide and prominent risk factors for the development of alcoholic liver disease (ALD). There are no FDA-approved medications to prevent or to treat any stage of ALD. Therefore, discovery of novel therapeutic strategies remains a critical need for patients with ALD. Relevant experimental animal models that simulate human drinking patterns and mimic the spectrum and severity of alcohol-induced liver path...
#1Shubha Ghosh Dastidar (University of Louisville)H-Index: 2
#2Ganapathy Jagatheesan (University of Louisville)H-Index: 5
Last.Daniel J. Conklin (University of Louisville)H-Index: 28
view all 4 authors...
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