Sara Martinez-Pascual
Organic chemistryEnzymeChemistryBiocatalysisImmobilized enzyme
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Publications 2
#1Jon Del ArcoH-Index: 4
Last. Jesús Fernández-LucasH-Index: 12
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The enzymatic synthesis of nucleotides offers several advantages over traditional multistep chemical methods, such as stereoselectivity, regioselectivity, enantioselectivity, simple downstream processing, and the use of mild reaction conditions. However, in order to scale up these bioprocesses, several drawbacks, such as the low enzyme stability and recycling, must be considered. Enzyme immobilization may overcome these cost-related problems by enhancing protein stability and facilitating the se...
5 CitationsSource
#1Javier AcostaH-Index: 2
#2Jon Del ArcoH-Index: 4
Last. Jesús Fernández-LucasH-Index: 12
view all 5 authors...
Biocatalysis reproduce nature’s synthetic strategies in order to synthesize different organic compounds. Natural metabolic pathways usually involve complex networks to support cellular growth and survival. In this regard, multi-enzymatic systems are valuable tools for the production of a wide variety of organic compounds. Methods: The production of different purine nucleosides and nucleoside-5′-monophosphates has been performed for first time, catalyzed by the sequential action of 2′-deoxyribosy...
6 CitationsSource