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Sara Emad El-Agamy
Ain Shams University
2Publications
1H-index
16Citations
Publications 2
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#1Sara Emad El-Agamy (Ain Shams University)H-Index: 1
#2Amal Kamal Abdel-Aziz (Ain Shams University)H-Index: 8
Last.Samar S. Azab (Ain Shams University)H-Index: 10
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Chemobrain refers to a common sequela experienced by a substantial subset of cancer patients exposed to chemotherapeutic treatment, a phenomenon that dramatically deteriorates the survivors’ quality of life and prevents them from restoring their pre-cancer life. This review is intended to address the current knowledge regarding the mechanisms underlying the pathophysiology of the chemobrain phenomenon, with special focus on the antineoplastic agent ‘’doxorubicin’’, which has been shown to be imp...
1 CitationsSource
#1Sara Emad El-Agamy (Ain Shams University)H-Index: 1
#2Amal Kamal Abdel-Aziz (Ain Shams University)H-Index: 8
Last.Samar S. Azab (Ain Shams University)H-Index: 10
view all 5 authors...
Chemobrain refers to a common sequelae experienced by 15–80% of cancer patients exposed to chemotherapeutics. The antineoplastic agent doxorubicin (DOX) has been implicated in a strenuous neurotoxicity manifested as decline in cognitive functions, most probably via cytokine-induced oxidative and nitrosative damage to brain tissues. Astaxanthin (AST), a naturally occurring carotenoid, is reputable for its outstanding antioxidant, anti-inflammatory, and antiapoptotic activities. Therefore, the aim...
15 CitationsSource
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