Match!
Rajikha Raja
The Mind Research Network
Diffusion MRIDementiaWhite matterDiffusion TractographyDiffusion Kurtosis Imaging
3Publications
2H-index
21Citations
What is this?
Publications 4
Newest
#1Rajikha RajaH-Index: 2
#2Arvind CaprihanH-Index: 4
Last. Vince D. CalhounH-Index: 2
view all 4 authors...
Source
#1Gary A. RosenbergH-Index: 63
Last. Arvind CaprihanH-Index: 30
view all 7 authors...
Alzheimer’s disease (AD) and vascular cognitive impairment and dementia (VCID) are major causes of dementia, and when combined lead to accelerated cognitive loss. We hypothesized that biomarkers of neurodegeneration and neuroinflammation could be used to stratify patients into diagnostic groups. Diagnosis of AD can be made biologically with detection of amyloid and tau proteins in the cerebrospinal fluid (CSF) and vascular disease can be identified with diffusion tensor imaging (DTI). We recruit...
Source
#1Rajikha Raja (The Mind Research Network)H-Index: 2
#2Gary A. Rosenberg (UNM: University of New Mexico)H-Index: 63
Last. Arvind Caprihan (The Mind Research Network)H-Index: 30
view all 3 authors...
Abstract Diffusion MRI studies characterizing the changes in white matter (WM) due to vascular cognitive impairment, which includes all forms of small vessel disease are reviewed. We reviewed the usefulness of diffusion methods in discriminating the affected WM regions and its relation to cognitive impairment. These studies were categorized based on the diffusion MRI techniques used. The most common method was the diffusion tensor imaging, whereas other methods included diffusion weighted imagin...
2 CitationsSource
#1Rajikha RajaH-Index: 2
#2Gary A. Rosenberg (UNM: University of New Mexico)H-Index: 63
Last. Arvind CaprihanH-Index: 30
view all 3 authors...
Abstract Blood-brain barrier (BBB) separates the systemic circulation and the brain, regulating transport of most molecules to protect the brain microenvironment. Multiple structural and functional components preserve the integrity of the BBB. Several imaging modalities are available to study disruption of the BBB. However, the subtle changes in BBB leakage that occurs in vascular cognitive impairment and Alzheimer's disease have been less well studied. Dynamic contrast enhanced magnetic resonan...
19 CitationsSource
1